Results 91 to 100 of about 4,647 (247)
Improvement of BsAPA Aspartic Protease Thermostability via Autocatalysis-Resistant Mutation [PDF]
, 2019 An aspartic protease gene (Bsapa) was cloned from Bispora sp. MEY-1 and expressed in Pichia pastoris. The recombinant BsAPA showed maximal activity at pH 3.0 and 75 °C and remained stable at 70 °C and below, indicating the thermostable nature of BsAPA ...
Xiaoyun Su (139853) +9 more
core +1 more source
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.This review is about material design based on engineering multilevel sites from theoretical calculation and synthetic routes to mechanism, structure–activity relationship, challenges and perspectives for boosting hydrogen production in alkaline electrolyte. Electrolytic water splitting is a clean, carbon‐free method for producing green hydrogen and has
Ke Zhang +9 more
wiley +1 more source
A recursive microfluidic platform to explore the emergence of chemical evolution
Beilstein Journal of Organic Chemistry, 2017 We propose that a chemically agnostic approach to explore the origin of life, using an automated recursive platform based on droplet microfluidics, could be used to induce artificial chemical evolution by iterations of growth, speciation, selection, and ...
David Doran +4 more
doaj +1 more source
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.Pyrolysis of FeOx/g‐C3N4 and ZIF‐8 is performed to introduce Fe single atom and pyridinic nitrogen vacancies onto N‐doped carbon. This modification enables the materials to efficiently extract electrons from ciprofloxacin (CIP) and activate dissolved oxygen. 100% of CIP was degraded within 1 min without adding any oxidant.
Jianyang Gao +5 more
wiley +1 more source
iMetaMed, EarlyView.This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu +7 more
wiley +1 more source
Asymmetric Synthesis with a Chiral Catalyst Generated from Asymmetric Autocatalysis [PDF]
, 2016 A new and efficient one-pot system of asymmetric catalysis is presented in which a chiral catalyst (5-pyrimidyl alkanol) self-improves its ee by asymmetric autocatalysis and then acts as a highly enantioselective chiral catalyst for other asymmetric ...
Itaru Sato (2053825) +4 more
core +1 more source
Entropy, 2013 Polymers of hydrogen cyanide and their hydrolysis products constitute a plausible, but still poorly understood proposal for early prebiotic chemistry on Earth.
Peter F. Stadler +5 more
doaj +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Preliminary steps toward artificial protocell computation [PDF]
, 2007 Protocells are hypothesised as a transitional phase in the origin of life, prior to the evolution of fully functional prokaryotic cells. The work reported here is being done in the context of the PACE project, which is investigating the fabrication of ...
McMullin, Barry +5 more
core
Prebiotic Competition between Information Variants, With Low Error Catastrophe Risks
Entropy, 2015 During competition for resources in primitive networks increased fitness of an information variant does not necessarily equate with successful elimination of its competitors.
Radu Popa, Vily Marius Cimpoiasu
doaj +1 more source