Results 81 to 90 of about 4,647 (247)

Physical autocatalysis driven by a bond-forming thiol-ene reaction. [PDF]

, 2014
Autocatalysis has been extensively studied because it is central to the propagation of living systems. Chemical systems which self-reproduce like living cells would offer insight into principles underlying biology and its emergence from inanimate matter.
Bissette, Andrew, Bissette, AJ, Fletcher, SP, Bissette, A, Odell, Barbara, Odell, B, Fletcher, S, Fletcher, Stephen   +7 more
core   +1 more source

Integrated spherical nucleic acid nanoreactor mobilizes targeted PD‐L1 proteolysis and cuproptosis for robust breast cancer immunotherapy

BMEMat, EarlyView.
This study provides an integrated spherical nucleic acid nanoreactor (denoted as AMCuD) for targeted PD‐L1 degradation and chemo‐dynamically enhanced cuproptosis to synergically elicit robust immunotherapy against the triple‐negative breast cancer (TNBC) growth, recurrence and metastasis.
Ningxi Li, Honglin Huang, Qianyi Zeng, Li Zeng, Ziman Yang, Jinyang Shen, Shun Li, Hong Yang, Yiyao Liu, Chunhui Wu   +9 more
wiley   +1 more source

Sunlight‐Driven Green Synthesis of Platinum Nanoparticles From Double‐Vacancy Halide Perovskite Precursors for Methanol Reforming

Chemistry – A European Journal, EarlyView.
Sunlight‐driven synthesis offers a green and energy‐efficient route to metallic nanoparticles. Here, double‐vacancy halide perovskites (Cs2PtX6, X = Cl, Br) act as photoactive precursors for the in‐situ formation of ultrasmall (< 3 nm) platinum nanoparticles under simulated sunlight at room temperature.
Kevin Mego, Saray Chacón‐Ruiz, Pedro Ruiz‐Campos, Herme G. Baldoví, Pedro Atienzar   +4 more
wiley   +1 more source

Simple models of oscillating polymerizations:Dimeric form autocatalysis [PDF]

, 2011
For two variable chemical oscillators, a simple strategy is to combine autocatalysis with a term including a binomial Michaelian denominator (constant+concentration). This strategy is applied in this paper to the context of polymerization reactions.
Perez Ortiz, J.A., Katime, I., Juan A. Pérez Ortiz, Eduardo Mendizábal, Mendizábal, E. M., Issa Katime   +5 more
core   +1 more source

The Asymmetric Self‐Replicative Alkylation of N‐Arylaldimines Using Organolithium Reagents

Chemistry – A European Journal, EarlyView.
Here, we report a new asymmetric autoinductive reaction; the addition of nBuLi to N‐arylaldimines to form chiral lithium amides. The reaction proceeds with full conversion and complete transfer of chirality, representing the first example of an asymmetric autoinductive reaction with organolithium reagents.
Anka Hagelschuer, Paco Visser, Ben L. Feringa   +2 more
wiley   +1 more source

Enantioselective Synthesis Induced by Chiral Crystal Composed of dl-Serine in Conjunction with Asymmetric Autocatalysis [PDF]

, 2016
Asymmetric autocatalysis initiated by chiral crystals containing racemic dl-serine was achieved. P- and M-crystals of dl-serine acted as the source of chirality of asymmetric autocatalysis to afford highly enantioenriched (>99.5% ee) (S)- and (R ...
Kenta Suzuki (204780), Tsuneomi Kawasaki (1269294), Taisuke Sasagawa (2202799), Kenso Soai (1269288), Mizuki Uchida (2202805), Kazuya Shiozawa (2202802)   +5 more
core   +1 more source

Synthesis and Biological Evaluation of Well‐Defined M6P(n)‐Modified Glycopeptides for Targeted Protein Degradation

Chemistry – A European Journal, EarlyView.
A synthetic methodology has been developed to prepare multifunctional M6P and M6Pn ligands of different valency. The glycopeptides were conjugated to cetuximab and then examined to mediate cellular uptake of fluorescently labeled EGFRvIII. Only cetuximab modified by glycopeptides having 3 or 6 M6P or M6Pn residues demonstrated greater uptake.
Patrycja Lenartowicz, Jan‐Willem H. Langenbach, Nataliia Voloshyna, David Aidukas, Arwin J. Brouwer, John A. W. Kruijtzer, Geert‐Jan Boons   +6 more
wiley   +1 more source

Modeling Alkylcopper Decomposition Pathway: Deciphering Pre‐Nucleation Processes for Metallic Cu Nanoparticles Synthesis

Chemistry – A European Journal, EarlyView.
Computational study reveals a two‐step decomposition of alkylcopper complexes into (partially) reduced Cu clusters, proposed as prenucleation species for Cu(0) nanoparticle synthesis. Cu‐hydride intermediates and multinuclear centers lower reaction barriers.
Marina Descoubes, Hélène Gérard
wiley   +1 more source

Theoretical Framework for Predicting Dynamic Covalent Exchange Based on Proton Affinities and Proton‐Transfer Assistance

Chemistry – A European Journal, EarlyView.
Proton‑transfer catalysis controls acylsemicarbazide dissociation, linking proton affinity to exchange kinetics and enabling predictive design of robust, tunable dynamic covalent networks. ABSTRACT We provide design principles for predicting bond exchange kinetics in acylsemicarbazide (ASC)‐based systems that can be applied to tuning the properties of ...
Siebe Lekanne Deprez, Stefan J. D. Maessen, Angelina N. van Dam, Celine Nieuwland, Pascal Vermeeren, Anja R. A. Palmans, Célia Fonseca Guerra   +6 more
wiley   +1 more source

Silica‐Supported Mononuclear Methyl‐Platinum Complexes Stabilized by Trimethylphosphine—Synthesis, Structure, and Reactions Under Reducing Conditions

Chemistry – A European Journal, EarlyView.
The article describes the synthesis and molecular transformations of a silica‐supported bis(phosphine)methylplatinum(II) complex under reactive (H2, CO) and inert gas atmospheres. The focus lies on the stabilizing effect of the sterically non‐demanding trimethylphosphine ligand, which alters the reactivity of the surface sites, compared to other ...
Lea S. Kopietz, Sven Schaefer, Oksana Storcheva, Gabriele Raudaschl‐Sieber, Johannes Bitzer, Wolfgang Kleist, Klaus Köhler   +6 more
wiley   +1 more source