Results 31 to 40 of about 1,124,846 (342)

Autoimmune hepatitis [PDF]

open access: yesNew England Journal of Medicine, 1996
Autoimmune hepatitis is an inflammatory liver disease in which the immune system is believed to orchestrate an immune attack onto the liver cell. Current knowledge suggests that both T helper 1 (TH1) and TH2 programmes are involved in the generation of the liver damage.
Vergani, D, Mieli-Vergani, G
openaire   +13 more sources

Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis [PDF]

open access: yes, 2010
Recent genetic studies have led to identification of numerous loci that are associated with susceptibility to autoimmune diseases. The strategy of using information from these studies has facilitated the identification of novel juvenile idiopathic ...
Barton, A.   +12 more
core   +1 more source

Combination therapy for management of pemphigus patients with unexpected therapeutic response to rituximab: A report of five cases

open access: yesClinical Case Reports, 2023
Key Clinical Message The immunosuppressant agents should be considered earlier in the course of treatment with rituximab, possibly after the unfavorable response at first cycle of treatment, especially in male patients and those with high BMI.
Zeinab Aryanian   +6 more
doaj   +1 more source

Burden of pemphigus vulgaris with a particular focus on women: A review

open access: yesInternational Journal of Women's Dermatology, 2022
Pemphigus vulgaris is a chronic autoimmune mucocutaneous blistering disorder. Apart from the disease itself, other aspects of patients’ life, including psychological, social, and financial, can be affected.
Nika Kianfar, MD-MPH   +3 more
doaj   +1 more source

Autoimmune Hepatitis [PDF]

open access: yesCurrent Pediatric Reviews, 2015
Autoimmune hepatitis (AIH) is a severe hepatopathy characterised by female preponderance, hypertransaminasaemia, elevated levels of immunoglobulin (IgG), presence of serum autoantibodies and, histologically, by interface hepatitis. AIH occurs both in adults and children, being particularly aggressive in the latter.
Longhi, Maria Serena   +2 more
openaire   +5 more sources

Global discovery of lupus genetic risk variant allelic enhancer activity

open access: yesNature Communications, 2021
Thousands of genetic variants have been associated with lupus, but causal variants and mechanisms are unknown. Here, the authors combine a massively parallel reporter assay with genome-wide ChIP experiments to identify risk variants with allelic enhancer
Xiaoming Lu   +15 more
doaj   +1 more source

Screening for type 1 diabetes-, thyroid-, gastric-, and adrenal-specific humoral autoimmunity in 529 children and adolescents with celiac disease at diagnosis identifies as positive one in every nine patients [PDF]

open access: yes, 2016
No abstract ...
Anania, Caterina   +9 more
core   +1 more source

Frontal fibrosing alopecia: An update on the hypothesis of pathogenesis and treatment

open access: yesInternational Journal of Women's Dermatology, 2019
Frontal fibrosing alopecia (FFA) is a relatively new scarring alopecia that is considered a variant of lichen planopilaris (LPP) with no recognized promising treatments. In this study, we tried to clarify the underlying signaling pathways and their roles
Soheil Tavakolpour, PhD   +5 more
doaj   +1 more source

Two asymptomatic facial erythematous macules in an adult male

open access: yesSkin Health and Disease, 2023
Pemphigus is a group of autoimmune bullous disorders with different types. Pemphigus foliaceous (PF) is a difficult‐to‐diagnosis disorder which shares clinical features with many dermatoses.
Kamran Balighi   +3 more
doaj   +1 more source

Clinical Characteristics and Treatment Outcomes of Scleromyxedema: A 10-Year Retrospective Survey

open access: yesCase Reports in Dermatology, 2022
Scleromyxedema is a rare but important mucinosis disorder of the skin that is presented with dermatological manifestations such as waxy papules, diffuse induration, and nondermatologic involvements like neurological and renal disorders.
Abtin Ansari   +6 more
doaj   +1 more source

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