Results 61 to 70 of about 1,025,565 (291)

Urinary metabolomic biomarker candidates for skeletal muscle wasting in patients with rheumatoid arthritis

Journal of Cachexia, Sarcopenia and Muscle, 2023
Background Rheumatoid arthritis (RA) is an autoimmune disease that affects the joints, leading to chronic synovial inflammation and local tissue destruction. Extra‐articular manifestations may also occur, such as changes in body composition.
Marianne S. Oliveira, Rafaela C.E. Santo, Jordana M.S. Silva, Paulo V.G. Alabarse, Claiton V. Brenol, Steve P. Young, Ricardo M. Xavier   +6 more
doaj   +1 more source

An antigen-driven B-cell response within the salivary glands of patients with Sjögren’s syndrome [PDF]

, 2002
Infection with a bacterium or virus induces the production of antibodies, specialised protein molecules that bind to and eliminate the microorganism.
Berek, C., Stott, D.I.
core  

Insulin gene polymorphisms in type I diabetes, Addison's disease and the polyglandular autoimmune syndrome type II [PDF]

, 2008
Background: Polymorphisms within the insulin gene can influence insulin expression in the pancreas and especially in the thymus, where self-antigens are processed, shaping the T cell repertoire into selftolerance, a process that protects from ß-cell ...
Ramos-Lopez, Elizabeth, Lange, Britta Kristina, Kahles, Heinrich, Willenberg, Holger S., Meyer, Gesine, Penna Martinez, Marissa, Reisch, Nicole, Hahner, Stefanie, Seissler, Jürgen, Badenhoop, Klaus   +9 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Mediterranean Diet Adherence and Acne Vulgaris Severity in an Iranian Population: A Case‐Control Study

Health Science Reports
Background and Aims Although the development of acne is influenced by a range of factors, emerging research suggests that dietary choices may also play a role in acne management.
Zeinab Aryanian, Ali Nikjan, Sama Heidari, Reza Omid, Vahide Lajevardi, Parvane Hatami, Hanie Babaie   +6 more
doaj   +1 more source

Non-coronary cardiac manifestations of systemic lupus erythematosus in adults: a comparative study

The Pan African Medical Journal, 2019
Cardiac manifestations develop in the majority of patients with systemic lupus erythematosus (SLE) at some time during the course of their disease.
Sameh Sayhi, Nour Gueddich, Rym Dhahri, Najeh Bousetta, Bilel Arfaoui, Nadia Ben Abdelhafidh, Faida Ajili, Bassem Louzir   +7 more
doaj   +1 more source

A case report of esophageal cancer in a patient with pemphigus vulgaris: A coincidence or something beyond that?

Cancer Reports, 2023
Background Pemphigus is a group of rare but serious autoimmune blistering disorders, affecting skin and mucus membrane. Different reports have been published in respect to the coexistence of pemphigus with neoplasms, especially lympho‐proliferative ones.
Kamran Balighi, Zeinab Aryanian, Shadi Balighi, Ifa Etesami, Parvaneh Hatami   +4 more
doaj   +1 more source

Autoimmune Epilepsy [PDF]

Neurotherapeutics, 2019
The field of autoimmune epilepsy has evolved substantially in the last few decades with discovery of several neural autoantibodies and improved mechanistic understanding of these immune-mediated syndromes. A considerable proportion of patients with epilepsy of unknown etiology have been demonstrated to have an autoimmune cause.
Khalil S, Husari, Divyanshu, Dubey
openaire   +2 more sources

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Immune dysregulation as a cause of autoinflammation in fragile X premutation carriers: link between FMRI CGG repeat number and decreased cytokine responses. [PDF]

, 2014
BackgroundIncreased rates of autoinflammatory and autoimmune disorders have been observed in female premutation carriers of CGG repeat expansion alleles of between 55-200 repeats in the fragile X mental retardation 1 (FMR1) gene.
Ashwood, Paul, Berman, Robert F, Careaga, Milo, Hagerman, Randi, Rose, Destanie, Tassone, Flora   +5 more
core   +2 more sources