Results 231 to 240 of about 9,492,165 (393)

Clinical overview on RASopathies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022
Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley   +1 more source

Association between autoimmune disease and neurodevelopmental disorder: a Mendelian randomization analysis. [PDF]

Ital J Pediatr
Qin J, Zhang Y, Hu R, Lin M, Yu R, Hua Y, Li Y.   +6 more
europepmc   +1 more source

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

Nature, 2003
H. Ueda, J. Howson, L. Esposito, J. Heward, H. Snook, Giselle Chamberlain, Daniel B. Rainbow, K. Hunter, Annabel N. Smith, G. Di Genova, M. Herr, I. Dahlman, F. Payne, D. Smyth, C. Lowe, R. Twells, S. Howlett, B. Healy, S. Nutland, H. Rance, Vincent H. Everett, L. Smink, A. Lam, H. Cordell, N. Walker, C. Bordin, John S Hulme, C. Motzo, F. Cucca, J. Hess, M. Metzker, J. Rogers, S. Gregory, A. Allahabadia, R. Nithiyananthan, E. Tuomilehto-Wolf, J. Tuomilehto, P. Bingley, K. Gillespie, D. Undlien, K. Rønningen, C. Guja, C. Ionescu-Tîrgoviste, D. Savage, A. Maxwell, D. Carson, C. Patterson, J. Franklyn, D. Clayton, L. Peterson, L. Wicker, J. Todd, S. Gough   +52 more
semanticscholar   +1 more source

Engineering the Immune Response to Biomaterials

Advanced Science, EarlyView.
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam, Mehran Bahrami, Einollah Sarikhani, Rumeysa Tutar, Yavuz Nuri Ertas, Faleh Tamimi, Ali Hedayatnia, Clotilde Jugie, Houman Savoji, Asma Talib Qureshi, Muhammad Rizwan, Chima V. Maduka, Nureddin Ashammakhi   +12 more
wiley   +1 more source

Autoimmune disease: a view of epigenetics and therapeutic targeting. [PDF]

Front Immunol
Mu S, Wang W, Liu Q, Ke N, Li H, Sun F, Zhang J, Zhu Z.   +7 more
europepmc   +1 more source

Enhancing Grasping Function with a Thermoresponsive Ionogel Adhesive Glove for Patients with Rheumatic Diseases

Advanced Science, EarlyView.
This study presents a novel portable grasp‐assist glove, weighing only 47 g. The glove integrates smart adhesive pads and a hands‐free control interface based on IMU, designed to aid rheumatic patients with impaired hand function. The system enables switchable adhesion with independent control and detection of user release intent.
Shiqiang Wang, Shiqing Liu, Jingfeng Zhang, Zhouyang Yu, Yifan Shao, Cong Zhao, Jiahong Ma, Xin Fu, Mengqi Yang, Lie Chen, Mingjie Liu, Li Wen   +11 more
wiley   +1 more source

Persistent discharge or edema after endoscopic sinus surgery in patients with chronic rhinosinusitis is associated with a type 1 or 3 endotype

International Forum of Allergy &Rhinology, Volume 13, Issue 1, Page 15-24, January 2023., 2023
Abstract Background Patients with chronic rhinosinusitis (CRS) may have persistence of polyps, discharge, or edema after endoscopic sinus surgery (ESS). Inflammation in CRS can be classified into three endotypes, with the presence of polyps associated with the type 2 endotype.
Eli Stein, Alexander L. Schneider, Regan Harmon, Samuel D. Racette, Abhita T. Reddy, Caroline P. E. Price, Julia H. Huang, Atsushi Kato, Stephanie Shintani‐Smith, David B. Conley, Kevin C. Welch, Robert C. Kern, Bruce K. Tan   +12 more
wiley   +1 more source

Immune checkpoint inhibitors in cancer patients with autoimmune disease: Safety and efficacy. [PDF]

Hum Vaccin Immunother
Le J, Sun Y, Deng G, Dian Y, Xie Y, Zeng F.   +5 more
europepmc   +1 more source

Dimethyl Itaconate Alleviates Escherichia coli‐Induced Endometritis Through the Guanosine‐CXCL14 Axis via Increasing the Abundance of norank_f_Muribaculaceae

Advanced Science, EarlyView.
The research findings indicate that dimethyl itaconate (DI) alleviates Escherichia coli (E. coli) induced endometritis by modulating the gut microbiota and enriching the abundance of norank_f_Muribaculaceae, thereby increasing the production of guanosine.
Yuhang He, Jiapei Cai, Xufeng Xie, Xinyu Zhang, Linkai Qu, Jiuxi Liu, Yongguo Cao   +6 more
wiley   +1 more source

Sickle cell and autoimmune disease: a double whammy. [PDF]

Haematologica
De Kreuk AM.
europepmc   +1 more source