Results 251 to 260 of about 9,492,165 (393)

Targeted Delivery of α‐ketoglutarate to Macrophages in Bone: A Novel Therapeutic Strategy for Improving Fracture Healing in Type 2 Diabetes

Advanced Science, EarlyView.
The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang, Jiahao Cao, Siqi Zhang, Hongli Chen, Xuebing Yu, Xinli Wang, Tianji Wang, Wei Cao, Wengang Dong, Xinsen Lin, Jia Li, Wei Lei, Yafei Feng   +12 more
wiley   +1 more source

Autoimmune disease and risk of lymphoma: analysis from real-world data and Mendelian randomization study. [PDF]

BMC Cancer
Zhan L, Chen S, Liu Y, Lu T, Yu Z, Wang X, Zhou X.   +6 more
europepmc   +1 more source

Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease. [PDF]

, 1994
Michael K. Racke, Adriana Bonomo, Dorothy E. Scott, B. Cannella, Arthur S. Levine, Cedric S. Raine, Ethan M. Shevach, Martin Röcken   +7 more
openalex   +1 more source

Hypogonadism and the risk of rheumatic autoimmune disease

Clinical Rheumatology, 2016
J. Baillargeon, S. Snih, M. Raji, R. Urban, G. Sharma, M. Sheffield-Moore, D. S. Lopez, G. Baillargeon, Y. Kuo   +8 more
semanticscholar   +1 more source

Mechanisms of Baicalin Alleviates Intestinal Inflammation: Role of M1 Macrophage Polarization and Lactobacillus amylovorus

Advanced Science, EarlyView.
Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang, Ruqing Zhong, Miao Zhou, Kai Li, Huiyuan Lv, Huixin Wang, Ye Xu, Dadan Liu, Qiugang Ma, Liang Chen, Hongfu Zhang   +10 more
wiley   +1 more source

CAR-T cell therapy embarks on autoimmune disease. [PDF]

Bone Marrow Transplant
Rampotas A, Richter J, Isenberg D, Roddie C.   +3 more
europepmc   +1 more source

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

Evaluating the association between autoimmune disease and normal tension glaucoma: a retrospective case-control study. [PDF]

BMC Ophthalmol
Becerra CMC, Funk RO, Kohli D, Hodge DO, Roddy GW.   +4 more
europepmc   +1 more source

Virus-induced autoimmunity: Molecular mimicry as a route to autoimmune disease

, 1989
Michael B. A. Oldstone
openalex   +1 more source

A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease. [PDF]

, 1992
Michael C. Sneller, Stephen E. Straus, Elaine S. Jaffe, Jonathan S. Jaffe, Thomas A. Fleisher, Maryalice Stetler‐Stevenson, Warren Strober   +6 more
openalex   +1 more source