Results 81 to 90 of about 9,974,127 (411)

Glycosylation in Autoimmune Diseases

, 2021
Autoimmune diseases are accompanied by changes in protein glycosylation, in both the immune system and target tissues. The best-studied alteration in autoimmunity is agalactosylation of immunoglobulin G (IgG), characterized primarily in rheumatoid arthritis (RA), and then detected also in systemic lupus erythematosus (SLE), inflammatory bowel disease ...
Ząbczyńska, Marta, Link-Lenczowski, Paweł, Pocheć, Ewa   +2 more
openaire   +4 more sources

Electrosmog and autoimmune disease [PDF]

Immunologic Research, 2016
Studies in mice have shown that environmental electromagnetic waves tend to suppress the murine immune system with a potency similar to NSAIDs, yet the nature of any Electrosmog effects upon humans remains controversial. Previously, we reported how the human Vitamin-D receptor (VDR) and its ligand, 1,25-dihydroxyvitamin-D (1,25-D), are associated with ...
Trevor G. Marshall, Trudy J. Rumann Heil
openaire   +3 more sources

NMDAR‐Antibody Encephalitis Diagnosed With Primary Central Nervous System Lymphoma: A Case Series

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT N‐methyl‐D‐aspartate receptor‐antibody encephalitis (NMDAR encephalitis) is one of the most common forms of autoimmune encephalitis, with a paraneoplastic relationship described in approximately 38%. Primary central nervous system lymphoma (PCNSL) is a rare hematologic malignancy that is not often considered as the underlying neoplasm in this ...
Soo Hyun Ahn, Cynthea Prima, Tae Min Kim, Soon‐Tae Lee, Kon Chu   +4 more
wiley   +1 more source

CTLA-4: a negative regulator of autoimmune disease. [PDF]

, 1996
CTLA-4, a CD28 homologue expressed on activated T cells, binds with high affinity to the CD28 ligands, B7-1 (CD80) and B7-2 (CD86). This study was designed to examine the role of CTLA-4 in regulating autoimmune disease.
Bluestone, JA, Karandikar, NJ, Miller, SD, Vanderlugt, CL, Walunas, TL   +4 more
core  

Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis [PDF]

, 2010
Recent genetic studies have led to identification of numerous loci that are associated with susceptibility to autoimmune diseases. The strategy of using information from these studies has facilitated the identification of novel juvenile idiopathic ...
Barton, A., British Society of Paediatric and Adolescent Rheumatology (BSPAR) Study Group, Childhood Arthritis Prospective Study (CAPS), Eyre, S., Flynn, E., Gardner-Medwin, J. [CAPS and BSPAR study groups], Hinks, A., Ke, X., Martin, P., Packham, J., Thomson, W., UKRAG Consortium, Worthington, J.   +12 more
core   +1 more source

Probiotic-derived extracellular vesicles: the next breakthrough in postbiotics for rheumatoid arthritis

Frontiers in Immunology
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic inflammation and joint damage. Emerging evidence highlights the role of gut and oral microbiota in RA pathogenesis, with microbial dysbiosis potentially exacerbating ...
Federica Dell’Atti, Federica Dell’Atti, Hugo Abreu, Hugo Abreu, Patrizia Malfa, Davide Raineri, Davide Raineri, Giuseppe Cappellano, Giuseppe Cappellano, Annalisa Chiocchetti, Annalisa Chiocchetti   +10 more
doaj   +1 more source

Hyposalivation in autoimmune diseases [PDF]

Rheumatology International, 2012
We have investigated the prevalence of dry mouth among patients with autoimmune diseases other than Sjögren's syndrome. One hundred and forty-four patients, excluding patients with primary Sjögren's syndrome, were enrolled in this study. The volume of saliva secreted was measured with the screening technique for estimation of salivary flow, which uses ...
Hiroya Koshiba, Kanako Furukawa, Etsuko Maeshima, Wataru Sakamoto, Shinichiro Maeshima   +4 more
openaire   +2 more sources

Relevance of Kappa and Lambda Free Light Chains in Autoimmune Astrocytopathy Associated With Anti‐GFAP Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction The kappa‐free light chain (κ‐FLC) index is known to be highly sensitive and specific for diagnosing multiple sclerosis (MS), while little is understood about lambda (λ)‐FLC. This study assessed the κ‐FLC and λ‐FLC indices in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.
Michael Levraut, Romain Marignier, Mikael Cohen, Jeanne Benoit, Cassandre Landes‐Chateau, Elisabeth Maillart, Marion Cremoni, Barbara Seitz‐Polski, Anne‐Laurie Pinto, Pauline Dumez, Jérôme Honnorat, Christine Lebrun‐Frenay   +11 more
wiley   +1 more source

Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis [PDF]

, 2006
Galectin (Gal)-1, an endogenous lectin found at sites of immune privilege, plays a critical role in the regulation of the immune response. Therapeutic administration of Gal-1 or its genetic delivery suppresses chronic inflammation in experimental models ...
Bianco, German Ariel, Ferrero, Mercedes, Juarez, Claudio P., Luna, José Domingo, Muiño, Juan Carlos, Rabinovich, Gabriel A., Romero, Marta D.   +6 more
core   +1 more source

The potential roles of herpesvirus and cytomegalovirus in the exacerbation of pemphigus vulgaris

Dermatology Practical & Conceptual, 2018
Background: Among exogenous etiologies, the critical role of microbial agents such as herpesviruses (HSV1/2) and cytomegalovirus (CMV) in triggering and flaring autoimmune conditions such as pemphigus vulgaris (PV) has been recently discovered ...
Fariba Mohammadi, Zahra Khalili, Sayed Mahdi Marashi, Amirhoushang Ehsani, Maryam Daneshpazhooh, Majid Teymoori-Rad, Kamran Balighi, Ahmad Nejati, Shohreh Shahmahmoodi, Shima Izadidakhrabadi, Hamidreza Mahmoudi, Pedram Noormohammadpour   +11 more
doaj   +1 more source