Results 1 to 10 of about 9,706,967 (334)

Roles of GM-CSF in the Pathogenesis of Autoimmune Diseases: An Update. [PDF]

Frontiers in Immunology, 2019
Granulocyte-macrophage colony-stimulating factor (GM-CSF) was first described as a growth factor that induces the differentiation and proliferation of myeloid progenitors in the bone marrow.
Adorini, Ahn, Alnek, Ananthakrishnan, Aram, Aricha, Basdeo, Bernasconi, Bezbradica, Bhattacharya, Bhattacharya, Bogunovic, Borriello, Campbell, Cao, Casciola-Rosen, Cheatem, Chiewchengchol, Choi, Chuang, Ciric, Codarri, Cook, Cook, Coombes, Croxford, Denson, Derouet, Dieckgraefe, Duhen, Egea, El-Behi, Enzler, Fernandes, Fillatreau, Fraussen, Fuchs, Ganesan, Ganesh, Gangi, Gao, Gathungu, Gaudreau, Ghosh, Gonzalez, Gopisetty, Hansen, Harrington, Hartmann, Hirota, Hirota, Hirota, Huang, Imitola, Jain, Kared, Karni, Kaskow, Katano, Katz, Kelly, Kenkel, King, King, Kister, Lebre, Lee, Lehtonen, Leizer, Li, Li, Li, Li, Makris, Marks, Matsuyama, Mausberg, McWilliams, Meriggioli, Midgley, Mikita, Mufazalov, Muranski, Nagane, Noster, Ortega, Parajuli, Pare, Pare, Park, Piper, Ponomarev, Poppensieker, Ramos-Levi, Rasouli, Reynolds, Roelofs, Rowin, Sakaguchi, Salehi, Samarpita, Scholz, Schutt, Serafini, Shang, Shapouri-Moghaddam, Sheng, Sheng, Sheng, Shiomi, Shiomi, Shiomi, Smith, Srenathan, Stojic-Vukanic, Surendar, Tavakolpour, Touil, Tsark, van de Laar, van Nieuwenhuijze, Vasu, Vincent, Vincent, Vogel, Waisman, Wicks, Wiggins-Dohlvik, Willeke, Xu, Xu, Yang, York, Zhang, Zhao   +134 more
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Variant of TYR and Autoimmunity Susceptibility Loci in Generalized Vitiligo. [PDF]

, 2010
BACKGROUND Generalized vitiligo is an autoimmune disease characterized by melanocyte loss, which results in patchy depigmentation of skin and hair, and is associated with an elevated risk of other autoimmune diseases. METHODS To identify generalized
Alain Taïeb, Alexandra J.D. Sufit, Andreas Overbeck, Anita Amadi-Myers, Anthony P. Weetman, Brand OJ, Christina M. Mailloux, David J. Gawkrodger, Dorothy C. Bennett, E. Helen Kemp, Giovanni Leone, Honda Y, Jo Lambert, Katherine Gowan, Khaled Ezzedine, Margaret R. Wallace, Mauro Picardo, Nanny van Geel, Pamela R. Fain, Paulene J. Holland, Richard A. Spritz, Saunie M. Hutton, Sheri L. Riccardi, Stanca A. Birlea, Thomas Jouary, Tripathi RK, Waerner T, Wang L, Wayne T. McCormack, Ying Jin   +29 more
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MicroRNA in autoimmunity and autoimmune diseases

Journal of Autoimmunity, 2009
MicroRNAs (miRNAs) are small conserved non-coding RNA molecules that post-transcriptionally regulate gene expression by targeting the 3' untranslated region (UTR) of specific messenger RNAs (mRNAs) for degradation or translational repression.
Department of Oral Surgery, Diagnostic Sciences, University of Florida, Gainesville, FL, USA ( host institution ), Pauley, Kaleb M., Cha, Seunghee, Chan, Edward K.L.   +4 more
openaire   +4 more sources

Autoimmune Disease Genetics [PDF]

Clinical and Developmental Immunology, 2012
Genetic risk factors play an important role in autoimmune disease susceptibility. Recent advances genotyping techniques, statistical methods, and the organization of large patient cohorts have facilitated explosive progress in this field, and our understanding of the genetic architecture of human autoimmunity is rapidly expanding.
Mohammed Tikly, Timothy B. Niewold, Shervin Assassi, George N. Goulielmos   +3 more
openaire   +3 more sources

Shared genetic variants suggest common pathways in allergy and autoimmune diseases. [PDF]

, 2016
BACKGROUND: The relationship between allergy and autoimmune disorders is complex and poorly understood. OBJECTIVE: To investigate commonalities in genetic loci and pathways between allergy and autoimmune diseases to elucidate shared disease mechanisms ...
Adnan Custovic, Alan James, Alexessander Couto Alves, Ananieva, Andersson, Angela Simpson, Bach, Barrett, Bergamaschi, Bhatt, Bønnelykke, Carla M.T. Tiesler, Chen, Chevalier, Clark, Cotsapas, Cotsapas, Craig E. Pennell, David Hinds, David P. Strachan, Dirkje S. Postma, Du, Elaine Fuertes, Elangovan, Eskil Kreiner, Farh, Ferreira, Ferreira, Franke, Fujita, Gerard H. Koppelman, Gohlke, Gudbjartsson, Han, Hans Bisgaard, Hinds, Hirota, Jeffery, Joel N. Hirschhorn, Johannes Waage, John Henderson, Jostins, Joyce Y. Tung, Klaus Bønnelykke, Koch, Kofler, Lango Allen, Lee, Li, Lloyd, Lude Franke, Maier, Manuel A. Ferreira, Marie Standl, Marjo-Riitta Jarvelin, Maurano, Mells, Moffatt, Nair, Nicholas Timpson, Nicole M. Warrington, Palmer, Paternoster, Pers, Petukhova, Pittet, Rabin, Rudwaleit, Sawcer, Sevelsted, Sirota, Stahl, Steinman, Susanne Brix, Tak, Takimoto, Terrados, Tune H. Pers, Urayama, Verhoef, Wang, Welter, Yan, Yoshida, Zhernakova   +84 more
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Carnosol Modulates Th17 Cell Differentiation and Microglial Switch in Experimental Autoimmune Encephalomyelitis [PDF]

, 2018
Medicinal plants as a rich pool for developing novel small molecule therapeutic medicine have been used for thousands of years. Carnosol as a bioactive diterpene compound originated from Rosmarinus officinalis (Rosemary) and Salvia officinalis, herbs ...
Fei Zhang, Guang-Xian Zhang, Juan-Juan Han, Li Zhao, Lin Zhu, Shuai Liu, Xing Li, Xing Li, Yuan Zhang, Yuan Zhang, Zhe-Zhi Wang   +10 more
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Eosinophils in Autoimmune Diseases [PDF]

Frontiers in Immunology, 2017
Eosinophils are multifunctional granulocytes that contribute to initiation and modulation of inflammation. Their role in asthma and parasitic infections has long been recognized. Growing evidence now reveals a role for eosinophils in autoimmune diseases.
Diny, Nicola L., Čiháková, Daniela, Rose, Noel   +2 more
openaire   +5 more sources

Does vitamin D play a role in autoimmune endocrine disorders? A proof of concept [PDF]

, 2017
In the last few years, more attention has been given to the "non-calcemic" effect of vitamin D. Several observational studies and meta-analyses demonstrated an association between circulating levels of vitamin D and outcome of many common diseases ...
Altieri, Barbara, Altieri, Vincenzo M, Balercia, Giancarlo, Barrea, Luigi, Bizzaro, Giorgia, Bizzaro, Nicola, Colao, Annamaria, Della Casa, Silvia, Mascitelli, Luca, Mathieu, Chantal, Muscogiuri, Giovanna, Pontecorvi, Alfredo, Ronchi, Cristina L, Savastano, Silvia, Tirabassi, Giacomo, Vallone, Carla V   +15 more
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Celiac Disease Autoimmunity [PDF]

Archivum Immunologiae et Therapiae Experimentalis, 2018
Celiac disease is an autoimmune condition triggered by the ingestion of gluten, the protein fraction of wheat, barley and rye. It is not simply an intestinal disease; it is multifactorial caused by many different genetic factors acting together with non-genetic causes.
Miguel Ángel López Casado, Pedro Lorite, Candelaria Ponce de León, Teresa Palomeque, Maria Isabel Torres   +4 more
openaire   +4 more sources

Electrosmog and autoimmune disease [PDF]

Immunologic Research, 2016
Studies in mice have shown that environmental electromagnetic waves tend to suppress the murine immune system with a potency similar to NSAIDs, yet the nature of any Electrosmog effects upon humans remains controversial. Previously, we reported how the human Vitamin-D receptor (VDR) and its ligand, 1,25-dihydroxyvitamin-D (1,25-D), are associated with ...
Trevor G. Marshall, Trudy J. Rumann Heil
openaire   +3 more sources