Results 121 to 130 of about 10,168,516 (390)

The study of factors associated with pregnancy outcomes in patients with systemic lupus erythematosus

BMC Research Notes, 2020
Objectives Systemic lupus erythematosus (SLE) is an autoimmune disease that can lead to unfavorable pregnancy complications in women. This study aimed to evaluate the factors associated with pregnancy outcomes in patients with SLE.
Batool Zamani, Mohammad Shayestehpour, Farifteh Esfahanian, Hossein Akbari   +3 more
doaj   +1 more source

The Role of Monocytes and Macrophages in Autoimmune Diseases: A Comprehensive Review

Frontiers in Immunology, 2019
Monocytes (Mo) and macrophages (Mϕ) are key components of the innate immune system and are involved in regulation of the initiation, development, and resolution of many inflammatory disorders. In addition, these cells also play important immunoregulatory
Wen-Tao Ma, Fei Gao, Kui Gu, De-kun Chen
semanticscholar   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

AB0630 PREGNANCY IN AUTOIMMUNE DISEASES: THE IMPACT OF PREGNANCY PLANNING ON REPRODUCTIVE OUTCOMES IN A MULTIDISCIPLINARY PRECONCEPTION OUTPATIENT CLINIC [PDF]

, 2023
C. Sieiro Santos, Berta Magallares, H. Park, H. Marco, Elisa Llurba, Montserrat Díaz, Stephanie Ros, Patricia Moya, J. L. Tandaipan, Cèsar Díaz‐Torné, Carla Pitarch, Susana Fernández, A. Laíz, J. Torguet, H. Codes, I. Castellví, Hèctor Corominas   +16 more
openalex   +1 more source

The Dynamic Interplay between the Gut Microbiota and Autoimmune Diseases

Journal of Immunological Research, 2019
The human gut-resident commensal microbiota is a unique ecosystem associated with various bodily functions, especially immunity. Gut microbiota dysbiosis plays a crucial role in autoimmune disease pathogenesis as well as in bowel-related diseases ...
Huihui Xu, Mei-jie Liu, Jinfeng Cao, Xiaoya Li, Danping Fan, Ya Xia, Xiangchen Lu, Jingtao Li, Dahong Ju, Hongyan Zhao   +9 more
semanticscholar   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Role of brain perfusion SPECT with 99mTc HMPAO in the assessment of response to drug therapy in patients with autoimmune vasculitis: a prospective study [PDF]

, 2015
BACKGROUND: The diagnosis of vasculitis in the brain remains a quite difficult achievement. To the best of our knowledge, there is no imaging method reported in literature which is capable of reaching to a diagnosis of vasculitis with very high ...
Anna Margherita Maffione, 2, Christos, Anagnostou, CIVITELLI, Liana, COLLORONE, SARA, DRUDI, Francesco Maria, FRANCIA, Ada, LIBERATORE, Mauro, Maria Cristina Marzola, 3, MEGNA, VALENTINA, MORREALE, MANUELA, Rubello, Domenico, Sotirios Chondrogiannis, 2   +11 more
core   +1 more source

Roles of GM-CSF in the Pathogenesis of Autoimmune Diseases: An Update

Frontiers in Immunology, 2019
Granulocyte-macrophage colony-stimulating factor (GM-CSF) was first described as a growth factor that induces the differentiation and proliferation of myeloid progenitors in the bone marrow.
Noushin Lotfi, R. Thome, N. Rezaei, Guang-Xian Zhang, A. Rezaei, A. Rostami, N. Esmaeil   +6 more
semanticscholar   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source