Results 241 to 250 of about 9,455,042 (324)

From MASLD to HCC: What's in the middle?

Heliyon
Metabolic dysfunction associated steatotic liver disease (MASLD) is a progressive pathological condition characterized by the accumulation of triglycerides within hepatocytes that causes histological changes, which, in the long run, might compromise ...
Alessia Provera, Cristina Vecchio, Anteneh Nigussie Sheferaw, Ian Stoppa, Deepika Pantham, Umberto Dianzani, Salvatore Sutti   +6 more
doaj  

Autoimmune Diseases and Molecular Mimicry in Tuberculosis. [PDF]

Biology (Basel)
Churilov LP, Normatov MG, Ling H, Zhuang M, Kudlay D, Starshinova A.   +5 more
europepmc   +1 more source

Sialochemistry of patients with autoimmune rheumatic disease with and without histological manifestations of Sjogren's syndrome.

, 1985
E B Tsianos, Athanasios G. Tzioufas, Anestis Mavridis, A K Sarras, Constantinos Papadimitriou, Orestes Tsolas, H M Moutsopoulos   +6 more
openalex   +1 more source

A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease. [PDF]

, 1992
Michael C. Sneller, Stephen E. Straus, Elaine S. Jaffe, Jonathan S. Jaffe, Thomas A. Fleisher, Maryalice Stetler‐Stevenson, Warren Strober   +6 more
openalex   +1 more source

DiffMC‐Gen: A Dual Denoising Diffusion Model for Multi‐Conditional Molecular Generation

Advanced Science, EarlyView.
DiffMC‐Gen, a dual‐diffusion model for 2D and 3D molecular generation, simultaneously optimizes multiple key objectives across the drug design process, enabling the generation of novel, target‐specific small‐molecule ligands with high therapeutic potential.
Yuwei Yang, Shukai Gu, Bo Liu, Xiaoqing Gong, Ruiqiang Lu, Jiayue Qiu, Xiaojun Yao, Huanxiang Liu   +7 more
wiley   +1 more source

Lymph nodes as gatekeepers of autoimmune diseases. [PDF]

RMD Open
O'Byrne AM, van Baarsen LGM.
europepmc   +1 more source

Changes in normal glycosylation mechanisms in autoimmune rheumatic disease. [PDF]

, 1992
John S. Axford, N. Sumar, Azita Alavi, David Isenberg, Adam Young, Katherine B. Bodman, I.M. Roitt   +6 more
openalex   +1 more source

Enhancing the Protein Stability of an Anticancer VHH‐Fc Heavy Chain Antibody through Computational Modeling and Variant Design

Advanced Science, EarlyView.
In this study, a computational pipeline is developed to systematically evaluate the conformational stability, disulfide bond reduction state, and aggregation and degradation tendencies of an anticancer VHH‐Fc fusion antibody. Based on the mechanistic insights, antibody variants with enhanced stability and increased yield are successfully designed. This
Yuan Fang, Menghua Song, Tianning Pu, Xiaoqing Song, Kailu Xu, Pengcheng Shen, Ting Cao, Yiman Zhao, Simon Hsu, Dongmei Han, Qiang Huang   +10 more
wiley   +1 more source

Bidirectional Mendelian randomization reveals associations between telomere length and autoimmune diseases. [PDF]

Trials
Jiang Q, Yu C, Zhu S, Liu Y, Ye M.
europepmc   +1 more source

Development of autoimmune disease in SCID mice populated with long-term "in vitro" proliferating (NZB x NZW)F1 pre-B cells. [PDF]

, 1992
Luc Reininger, T Radaszkiewicz, Marie H. Kosco, Fritz Melchers, A Rolink   +4 more
openalex   +1 more source