Results 271 to 280 of about 767,890 (335)

Ophthalmological manifestations in autoimmune diseases: Overcoming diagnostic and therapeutic challenges. [PDF]

World J Exp Med
El Kaouri I, Deligiannis I, Bakopoulou K, Sdralis PP, Shoumnalieva-Ivanova V, Shumnalieva R, Velikova T.   +6 more
europepmc   +1 more source

The effects of magnesium supplementation in autoimmune rheumatic diseases

Motti Haimi, Aaron Lerner, Jozélio Freire de Carvalho, Carina Benzvi   +3 more
openalex   +1 more source

Intestinal Neutral Ceramidase Deficiency Triggers Regulatory T Cell Response via Gd3 to Protect the Host from Intestinal Inflammation

Advanced Science, EarlyView.
Deletion of ASAH2 in intestinal epithelial cells induces the accumulation of ganglioside GD3 via regulating ST8SIA1. GD3 is identified as the glycolipid ligand for the inhibitory receptor Siglec‐E on macrophages. GD3/Siglec‐E ligation polarizes macrophages and promotes the proliferation of colonic ST2+ T regulatory cells via the induction of IL‐33. The
Zhishan Xu, Chao Lei, Mukesh K Sriwastva, Ting Wang, Amanguli Tuohongerbieke, Xiaotong Song, Collin Noud, Shannon Derkson, Yi Tan, Gerald Dryden, Craig J McClain, Zhongbin Deng   +11 more
wiley   +1 more source

Chronic obstructive pulmonary disease (COPD) and autoimmune diseases: unravelling complex interactions. [PDF]

Ann Med
Ceasovschih A, Șorodoc V, Balta A, Constantin M, Morărașu BC, Diaconu AD, Alexa RE, Asaftei A, Pavel-Tanasa M, Rusu-Zota G, Corlăteanu A, Hardavella G, Șorodoc L.   +12 more
europepmc   +1 more source

Identifying Early Pulmonary Complications in a Cohort of Egyptian Patients with Systemic Autoimmune Rheumatic Diseases

M. Hashem, M. Hanafy, Ahmed Kabil, Hesham Hamoud   +3 more
openalex   +1 more source

Puerarin Targets MIC19 to Suppress Mitochondrial Metabolism of Tumor‐Infiltrating Tregs and Enhance Anti‐tumor Immunity

Advanced Science, EarlyView.
Puerarin targets mitochondrial MIC19 in tumor‐infiltrating Tregs, impairing their immunosuppressive function and enhancing antitumor immunity. This study uncovers the metabolic dependency of tumor‐infiltrating Tregs and highlights a potential metabolic‐targeted immunotherapeutic strategy for liver cancer. Abstract Regulatory T cells (Tregs) are pivotal
Yu Li, Ziyan Song, Jianjun Ding, Yiheng Zhou, Tianning Huang, Qufei Qian, Miao Yu, Wenzhao Chen, Jiazheng Liu, Ling Lu, Qiuyang Chen   +10 more
wiley   +1 more source

Global prevalence of autoimmune diseases in turner syndrome: a systematic review and meta-analysis. [PDF]

Ann Med
Hwang S, Park Y, Moon H, Kim K, Yoo S, Cho SY, Kwon Y, Kim WK, Kim YH.   +8 more
europepmc   +1 more source

Metabolic Reprogramming of T Cells by Dual UCP2 and IL‐17 Blockade Enhances Immunity Against Pancreatic Cancer

Advanced Science, EarlyView.
This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu, Chun‐Chieh Yeh, Tsai‐Chen Wu, Chia‐Hsin Lin, Yi‐Ting Kuo, Yoichiro Iwakura, Yuan‐Ji Day, Charles Drake, Vedran Radojcic, Ying‐Chyi Song, Heng‐Hsiung Wu, Hung‐Rong Yen   +11 more
wiley   +1 more source

Innovations in immunotherapy for autoimmune diseases: recent breakthroughs and future directions. [PDF]

Front Immunol
Alsayb MA.
europepmc   +1 more source