Results 271 to 280 of about 9,455,042 (324)
The role of BATF in immune cell differentiation and autoimmune diseases. [PDF]
Wang X+8 more
europepmc +1 more source
The study identified sortilin as a promising LTR, enabling targeted degradation of oncogenic proteins through an mRNA‐encoded MedTAC strategy. In a mouse model, MedTACPTK7 reduced PTK7 by up to 80%, extended survival, and showed excellent pharmacokinetics without toxicity, providing a scalable platform for targeted therapies.
Xin Chang+8 more
wiley +1 more source
Sex-specific and regional differences in the prevalence of diagnosed autoimmune diseases in Germany, 2022. [PDF]
Akmatov MK+3 more
europepmc +1 more source
Polyphenols in the treatment of autoimmune diseases.
H. Khan+8 more
semanticscholar +1 more source
This study develops lipid nanoparticle‐encapsulated mRNA‐encoding antibodies (mRNab‐LNPs) targeting CD19, demonstrating robust anti‐CD19 antibody production in vivo. Intramuscular injection of mRNab‐LNPs reduces CD19+ B and plasma cells in lupus and rheumatoid arthritis mice, significantly alleviating histopathological changes and tissue injuries of ...
Chipeng Guo+10 more
wiley +1 more source
Immune Repertoires in Various Dermatologic and Autoimmune Diseases. [PDF]
Terhaar H+5 more
europepmc +1 more source