Haematopoietic stem cell transplantation for severe autoimmune diseases in children: A review of current literature, registry activity and future directions on behalf of the autoimmune diseases and paediatric diseases working parties of the European Society for Blood and Marrow Transplantation [PDF]
, 2022 Although modern clinical management strategies have improved the outcome of paediatric patients with severe autoimmune and inflammatory diseases over recent decades, a proportion will experience ongoing or recurrent/relapsing disease activity despite ...
The EBMT Autoimmune Diseases (ADWP) and Paediatric Diseases (PDWP) Working Parties
core
Memory CD4+ T Cells in Immunity and Autoimmune Diseases
Cells, 2020 CD4+ T helper (Th) cells play central roles in immunity in health and disease. While much is known about the effector function of Th cells in combating pathogens and promoting autoimmune diseases, the roles and biology of memory CD4+ Th cells are complex
Itay Raphael +2 more
semanticscholar +1 more source
Hashimoto's thyroiditis and autoimmune gastritis [PDF]
, 2017 The term "thyrogastric syndrome" defines the association between autoimmune thyroid disease and chronic autoimmune gastritis (CAG), and it was first described in the early 1960s.
Brusca, Nunzia +6 more
core +5 more sources
HLA-B27 Positivity: associated health implications [PDF]
, 2011 HLA-B27 positivity makes the onset of autoimmune diseases such as uveitis, ankylosing spondylitis and Crohn's disease more likely to occur. Ankylosing spondylitis and Crohn's disease are two types of HLA-B27 positive diseases that demonstrate a direct ...
Cox, C. L. +4 more
core +1 more source
Cytokine and autoantibody clusters interaction in systemic lupus erythematosus
Journal of Translational Medicine, 2017 Background Evidence supports the existence of different subphenotypes in systemic lupus erythematosus (SLE) and the pivotal role of cytokines and autoantibodies, which interact in a highly complex network.
Yovana Pacheco +11 more
doaj +1 more source
Clinical Case Reports, 2021 Thrombocytosis is an unusual side effect of all‐trans retinoic acid (ATRA) treatment that occurs in some patients with acute promyelocytic leukemia (APL).
Maryam Habibi +2 more
doaj +1 more source
Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases
Arthritis & Rheumatology, 2020 Clinical heterogeneity, a hallmark of systemic autoimmune diseases, impedes early diagnosis and effective treatment, issues that may be addressed if patients could be classified into groups defined by molecular pattern.
G. Barturen +130 more
semanticscholar +1 more source
Serotonin: A Potent Immune Cell Modulator in Autoimmune Diseases
Frontiers in Immunology, 2020 Serotonin, also known as 5-hydroxytryptamine (5-HT) is a signaling mediator that regulates emotion, behavior, and cognition. Previous studies have focused more on the roles of 5-HT in the central nervous system (CNS).
Minjie Wan +4 more
semanticscholar +1 more source
The microbiome in autoimmune diseases
Clinical and Experimental Immunology, 2019 The microbiome is represented by microorganisms which live in a symbiotic way with the mammalian. Microorganisms have the ability to influence different physiological aspects such as the immune system, metabolism and behaviour.
F. De Luca, Y. Shoenfeld
semanticscholar +1 more source
Two cases of neglected leishmaniasis with marked facial disfigurement: A diagnostic conundrum
Clinical Case Reports, 2023 Key Clinical Message There is a need to pay more attention to cutaneous leishmaniasis in endemic regions which may mimic other dermatoses and treatment should be initiated with a strong clinical suspicion even without any histopathologic or PCR ...
Zeinab Aryanian +5 more
doaj +1 more source