Serotonin: A Potent Immune Cell Modulator in Autoimmune Diseases
Serotonin, also known as 5-hydroxytryptamine (5-HT) is a signaling mediator that regulates emotion, behavior, and cognition. Previous studies have focused more on the roles of 5-HT in the central nervous system (CNS).
Minjie Wan+4 more
semanticscholar +1 more source
Cytokine and autoantibody clusters interaction in systemic lupus erythematosus
Background Evidence supports the existence of different subphenotypes in systemic lupus erythematosus (SLE) and the pivotal role of cytokines and autoantibodies, which interact in a highly complex network.
Yovana Pacheco+11 more
doaj +1 more source
Thrombocytosis is an unusual side effect of all‐trans retinoic acid (ATRA) treatment that occurs in some patients with acute promyelocytic leukemia (APL).
Maryam Habibi+2 more
doaj +1 more source
Advanced Biophotonics techniques for cell and molecules manipulation associated with cancer and autoimmune diseases: the role of optical tweezers [PDF]
Biophotonic techniques are growing in rapid rhythms enabling the monitoring of subcellular structures and non-invasive theranostic interventions in cancer and autoimmune diseases. The integration of Biophotonics with nanotechnology and biosensors brings a revolution in the micro- and nano-world with new optical tools.
arxiv
Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis [PDF]
Recent genetic studies have led to identification of numerous loci that are associated with susceptibility to autoimmune diseases. The strategy of using information from these studies has facilitated the identification of novel juvenile idiopathic ...
Barton, A.+12 more
core +1 more source
Two cases of neglected leishmaniasis with marked facial disfigurement: A diagnostic conundrum
Key Clinical Message There is a need to pay more attention to cutaneous leishmaniasis in endemic regions which may mimic other dermatoses and treatment should be initiated with a strong clinical suspicion even without any histopathologic or PCR ...
Zeinab Aryanian+5 more
doaj +1 more source
Enhancing Medical Image Segmentation: Optimizing Cross-Entropy Weights and Post-Processing with Autoencoders [PDF]
The task of medical image segmentation presents unique challenges, necessitating both localized and holistic semantic understanding to accurately delineate areas of interest, such as critical tissues or aberrant features. This complexity is heightened in medical image segmentation due to the high degree of inter-class similarities, intra-class ...
arxiv
Helminth Therapy: A Promising Approach to Treating Crohn's Disease and Asthma [PDF]
Increasing rates of autoimmune diseases, such as asthma and Crohn’s disease, have become a major concern in industrialized countries. One potential cause for the rising rates of autoimmune diseases in humans, is the disconnected relationship to parasites
Szaszkiewicz, Joshua Ethan
core +2 more sources
The Role of Calcium–Calcineurin–NFAT Signaling Pathway in Health and Autoimmune Diseases
Calcium (Ca2+) is an essential signaling molecule that controls a wide range of biological functions. In the immune system, calcium signals play a central role in a variety of cellular functions such as proliferation, differentiation, apoptosis, and ...
Yune-Jung Park+3 more
semanticscholar +1 more source
Background Pemphigus is a group of rare but serious autoimmune blistering disorders, affecting skin and mucus membrane. Different reports have been published in respect to the coexistence of pemphigus with neoplasms, especially lympho‐proliferative ones.
Kamran Balighi+4 more
doaj +1 more source