Results 131 to 140 of about 49,941 (320)
Bifurcations and multi-stability in a model of cytokine-mediated autoimmunity [PDF]
This paper investigates the dynamics of immune response and autoimmunity with particular emphasis on the role of regulatory T cells (Tregs), T cells with different activation thresholds, and cytokines in mediating T cell activity. Analysis of the steady states yields parameter regions corresponding to regimes of normal clearance of viral infection ...
arxiv +1 more source
Autoimmune causes of encephalitis syndrome in Thailand: prospective study of 103 patients [PDF]
Background: Data on encephalitis in Thailand have not been completely described. Etiologies remain largely unknown. We prospectively analyzed 103 Thai patients from 27 provinces for the causes of encephalitis using clinical, microbiological and ...
Callahan, Michael+8 more
core +1 more source
ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by progressive neurodegeneration and focal demyelinated lesions. Traditionally considered an autoimmune disease, MS is driven by the immune system's attack on CNS myelin, resulting in cumulative disability.
Volker Siffrin
wiley +1 more source
The role of tunable activation thresholds in the dynamics of autoimmunity [PDF]
It has been known for some time that human autoimmune diseases can be triggered by viral infections. Several possible mechanisms of interactions between a virus and immune system have been analysed, with a prevailing opinion being that the onset of autoimmunity can in many cases be attributed to "molecular mimicry", where linear peptide epitopes ...
arxiv
AI-Based Decadal Predictive Analysis of Twenty Infectious Diseases in China with an Improved BSTS-MCMC Model [PDF]
This study embarks on a comprehensive exploration of the decadal trends and future trajectories of twenty distinct infectious diseases in China from 1998 to 2021. A refined Hybrid Bayesian Structural Time Series (BSTS)-Markov Chain Monte Carlo (MCMC) model is employed, intertwining with Long Short-Term Memory (LSTM) networks to dissect intricate ...
arxiv
Diagnosis and treatment of paraneoplastic neurological disorders [PDF]
In about two thirds of cases, patients with paraneoplastic neurological disorders present to the neurologist without a known tumor. Due to the ongoing immune response, this tumor tends to stay biologically relatively benign, and therefore difficult to ...
Graus, F., Voltz, R.
core +1 more source
Autoimmune Encephalitis in Brief
This article is an Editorial and does not include an Abstract.
Man Amanat, Mona Salehi, Nima Rezaei
openaire +3 more sources
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen+10 more
wiley +1 more source
The Laboratory Diagnosis of Autoimmune Encephalitis [PDF]
Autoimmune encephalitis is a group of encephalitis syndromes that cause altered mentality, memory decline, or seizures in association with the presence of serum and cerebrospinal fluid (CSF) autoantibodies (auto-Abs). An early diagnosis enables early treatments. The detection of auto-Abs is a confirmatory diagnosis.
Sang Kun Lee, Soon-Tae Lee
openaire +3 more sources
Single‐Cell Metabolic Labeling Probe for Diagnosing Tuberculous Meningitis: A Case Report
This study reports the first clinical use of a single‐cell metabolic labeling probe for tuberculosis for diagnosing tuberculous meningitis, which rapidly and accurately detected Mycobacterium tuberculosis in cerebrospinal fluid. The patient's satisfactory therapeutic outcome highlights single‐cell metabolic labeling probe for tuberculosis's potential ...
Jiahao Wang+5 more
wiley +1 more source