Results 141 to 150 of about 485,527 (247)

Modulation of Cytokines and Immune Cells by Plasma Exchange in Patients With Certain Autoimmune Neurological Diseases

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
ABSTRACT Objective Therapeutic plasma exchange (TPE) plays a crucial role in the management of autoimmune neurological disorders, although its effects on cytokines and immune cells are not fully understood. This study aimed to investigate the impact of TPE on immune cell subsets, cytokine levels, and immunoglobulins. Methods A total of 85 patients with
Wanquan Xu, Shuting Chai, Gang Liu, Fei Tian, Weibi Chen, Dawei Shan, Yan Zhang   +6 more
wiley   +1 more source

Varicella Zoster Virus Infection: Clinical Features, Molecular Pathogenesis, Treatment, and Prevention

MedComm, Volume 7, Issue 3, March 2026.
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng, Honghao Song, Tianying Li, Yuqing Ma, Chen Yan, Yuhan Cao, Kaiqiang Sun, Chaofeng Han, Hongbin Yuan   +8 more
wiley   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Prolonged Anti‐Zic4 Antibody–Positive Cerebellar Degeneration Following COVID‐19 Infection

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
Serial MRI and SPECT revealed progressive cerebellar atrophy and worsening hypoperfusion over 2 years, despite partial clinical stabilization. These findings highlight radiological progression that exceeds symptom severity in post‐COVID anti‐Zic4 antibody–associated cerebellar degeneration.
Risa Suzuki‐Yamamoto, Asuka Nakajima, Tsuyoshi Furuya, Takahiro Koinuma, Atsuhito Fuse, Hiroto Eguchi, Yasushi Shimo   +6 more
wiley   +1 more source

A case of relieving thymoma after conservative management of anti‐gamma‐aminobutyric acid receptor type A encephalitis

Thoracic Cancer
Anti‐gamma‐aminobutyric acid receptor type A (GABAA) encephalitis is a relatively rare autoimmune encephalitis, and often associated with thymoma. Here, a 44‐year‐old female was diagnosed as having a thymoma with autoimmune encephalitis.
Yanmei Li, Ning Xie
doaj   +1 more source

Catatonia an Unexpected Side Effect of Electroconvulsive Therapy: A Case Report

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
This case report highlights an unexpected development of catatonia following electroconvulsive therapy in a patient with schizoaffective disorder. The catatonia resolved promptly after discontinuing psychotropic interventions, emphasizing the need for careful monitoring during ECT, especially in patients with complex psychiatric histories.
Fatemeh sheikhmoonesi, Behnam Abbasi, Tahoura Sedighi Barforoushi, Ebrahim Khoshnama   +3 more
wiley   +1 more source

Acute mania and psychosis potentially triggered by St John's wort

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Abstract Background St John's wort (SJW) is widely used as an herbal supplement for depressive symptoms and is generally regarded as safe. However, although extremely rare, manic and psychotic reactions have been reported, typically in individuals taking high doses, using psychotropic agents, or having a psychiatric history. Case Presentation We report
Daisuke Yoshioka, Takehiko Yamanashi, Masaaki Iwata   +2 more
wiley   +1 more source

A case of diverse psychiatric and functional impairments following immune checkpoint inhibitor therapy

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Abstract Background Immune checkpoint inhibitors (ICIs) can cause a range of immune‐related adverse events (irAEs), including rare neuropsychiatric complications. However, these events often present with diverse and non‐specific symptoms, making diagnosis difficult.
Takako Ikegami, Ryoichi Sadahiro, Junji Yamaguchi, Eri Nishikawa, Saho Wada, Tatsuto Terada, Rika Nakahara, Hiromichi Matsuoka   +7 more
wiley   +1 more source

Characteristics, Motivation, and Challenges of Global Research on Dengue Vaccination

Reviews in Medical Virology, Volume 36, Issue 2, March 2026.
ABSTRACT Due to the sharp increase in dengue infections in recent years, developing effective and regionally adapted vaccines is imperative. This requires research strategies aimed at vaccines that are free of side effects and effective for all four serotypes.
Doris Klingelhöfer, Markus Braun, Isabelle M. Kramer, Christina A. Naser, David A. Groneberg, Dörthe Brüggmann   +5 more
wiley   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, Volume 183, Issue 6, Page 1271-1287, March 2026.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source