Results 51 to 60 of about 51,530 (306)

Comparison of commercial and in-house tissue-based and cell-based assays for the detection of autoantibodies targeting neuronal surface proteins: a prospective cohort study

open access: yesFrontiers in Immunology
IntroductionThe detection of antibodies targeting neuronal antigens is a keystone for the diagnosis of autoimmune encephalitis (AE) and paraneoplastic neurological syndromes (PNS).
David Goncalves   +17 more
doaj   +1 more source

The chemokine receptor CXCR2 and coronavirus-induced neurologic disease. [PDF]

open access: yes, 2013
Inoculation with the neurotropic JHM strain of mouse hepatitis virus (MHV) into the central nervous system (CNS) of susceptible strains of mice results in an acute encephalomyelitis in which virus preferentially replicates within glial cells while ...
Akwa   +172 more
core   +1 more source

Mimics of Autoimmune Encephalitis

open access: yesNeurology Neuroimmunology & Neuroinflammation, 2023
The clinical criteria for autoimmune encephalitis (AE) were proposed by Graus et al. in 2016. In this study, the AE criteria were validated in the real world, and common AE mimics were described. In addition, criteria for probable anti-LGI1 encephalitis were proposed and validated.In this retrospective cohort study, patients referred to our national ...
Robin W. Van Steenhoven   +15 more
openaire   +2 more sources

Differential regulation of innate and adaptive immune responses in viral encephalitis. [PDF]

open access: yes, 2004
Viral encephalitis is a global health concern. The ability of a virus to modulate the immune response can have a pivotal effect on the course of disease and the fate of the infected host. In this study, we sought to understand the immunological basis for
Buchmeier, Michael J   +3 more
core   +1 more source

Hippocampal epileptogenesis in autoimmune encephalitis [PDF]

open access: yesAnnals of Clinical and Translational Neurology, 2019
AbstractObjectiveAutoantibody‐mediated forms of encephalitis (AE) include neurological disorders characterized by subacute memory loss, movement disorders, and, often, frequent, focal epileptic seizures. Yet, the electrophysiological effects of these autoantibodies on neuronal function have received little attention.
Arjune Sen   +18 more
openaire   +6 more sources

Promoting remyelination through cell transplantation therapies in a model of viral-induced neurodegenerative disease. [PDF]

open access: yes, 2019
Multiple sclerosis (MS) is a central nervous system (CNS) disease characterized by chronic neuroinflammation, demyelination, and axonal damage. Infiltration of activated lymphocytes and myeloid cells are thought to be primarily responsible for white ...
Adami   +99 more
core   +1 more source

Autoimmune causes of encephalitis syndrome in Thailand: prospective study of 103 patients [PDF]

open access: yes, 2013
Background: Data on encephalitis in Thailand have not been completely described. Etiologies remain largely unknown. We prospectively analyzed 103 Thai patients from 27 provinces for the causes of encephalitis using clinical, microbiological and ...
Callahan, Michael   +8 more
core   +1 more source

Neural Surface Antibodies and Neurodegeneration: Clinical Commonalities and Pathophysiological Relationships

open access: yesBiomedicines, 2023
Autoimmune encephalitis and neurodegenerative disorders share several clinical features, including behavioural and psychiatric manifestations, cognitive impairment, sleep and movement disorders.
Maria Pia Giannoccaro   +5 more
doaj   +1 more source

Minimal breast milk transfer of rituximab, a monoclonal antibody used in neurological conditions. [PDF]

open access: yes, 2020
ObjectiveTo determine the transfer of rituximab, an anti-CD20 monoclonal antibody widely used for neurologic conditions, into mature breast milk.MethodsBreast milk samples were collected from 9 women with MS who received rituximab 500 or 1,000 mg ...
Anderson, Annika   +10 more
core   +1 more source

NMDAR‐Antibody Encephalitis Diagnosed With Primary Central Nervous System Lymphoma: A Case Series

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT N‐methyl‐D‐aspartate receptor‐antibody encephalitis (NMDAR encephalitis) is one of the most common forms of autoimmune encephalitis, with a paraneoplastic relationship described in approximately 38%. Primary central nervous system lymphoma (PCNSL) is a rare hematologic malignancy that is not often considered as the underlying neoplasm in this ...
Soo Hyun Ahn   +4 more
wiley   +1 more source

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