Results 91 to 100 of about 107,589 (249)

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

Soluble B7‐H6 as a Novel Diagnostic Biomarker for Post‐Hepatitis B Cirrhosis: A Clinical Value Study

Journal of Clinical Laboratory Analysis, EarlyView.
This study investigates the potential of soluble B7‐H6 (sB7‐H6) as a novel diagnostic biomarker for post‐hepatitis B cirrhosis. The infographic visually presents the following key points: (1) Liver Disease Progression: Chronic hepatitis B (CHB) progresses to liver cirrhosis (LC), with serum sB7‐H6 levels increasing stepwise as the disease advances. (2)
Kaiyong Chen, Luxuan Yang, Huaiwu Fu, Lei Cao, Zhu Li   +4 more
wiley   +1 more source

Isoniazid‐Related Secondary Drug‐Induced Autoimmune Hepatitis in a Patient Diagnosed With Ankylosing Spondylitis and Tuberculous Lymphadenitis: A Case Report

Clinical Case Reports
Autoimmune hepatitis is a type of chronic hepatitis that is usually progressive, has unknown etiology, and can occur at any age. In the present case, drug‐associated autoimmune hepatitis (DIAIH) was discussed, and DIAIH secondary to isoniazid (INH) was ...
Murat AY, Erhan Bozkurt
doaj   +1 more source

Study of Risk Factors and Image Findings of Isolated Abdominal Incidentally Detected Aortic Dissection

Journal of Clinical Ultrasound, Volume 53, Issue 3, Page 429-435, March/April 2025.
We detect the risk factors and image characteristics of incidentally detected IAAD. Independent risk factors of IAAD included fatty liver and smoking. In the ultrasound findings of IAAD, an intimal flap was frequently observed. In the CT scan, displacement of intimal calcifications was frequently observed. For suspected IAAD, the abdominal aorta should
Hiromasa Tsubouchi, Hidenori Onishi, Koji Maeno, Masaya Nakagaichi, Ikue Tsukushi, Youichi Kitano, Yoshitaka Makino, Hiroyuki Hayashi, Hidekazu Terasawa, Hiroko Kabuto, Toshihiro Misawa, Taku Sanada, Azusa Hisada, Kazuo Notsumata, Kazuhiro Okafuji, Osamu Yamamura   +15 more
wiley   +1 more source

Immunology Highlights of Four Major Idiosyncratic DILI Subtypes Verified by the RUCAM: A New Evidence-Based Classification

Livers
Conventionally, drug-induced liver injury (DILI) exists in two types: idiosyncratic and intrinsic. Both types are classified as non-immune disorders, thereby ignoring that some iDILI cases may have an immune or autoimmune background that requires a ...
Rolf Teschke
doaj   +1 more source

Diagnostic Accuracy of Shear Wave Elastography for the Assessment of Congestive Liver Disease in Patients With Structural Heart Disease

Journal of Clinical Ultrasound, EarlyView.
Shear wave elastography demonstrated moderate diagnostic accuracy for detecting congestive liver disease in patients with structural heart disease. Increased liver stiffness was associated with echocardiographic markers of venous congestion, supporting the concept that elastography may serve as a noninvasive marker of cardiohepatic interaction ...
Edinéia Camargo Dziadzio, Maria Angelica Jungles Malikoski, Eduardo Henrique Bonotto, Sandra Monica Tochetto, Marco Stephan Lofrano‐Alves   +4 more
wiley   +1 more source

Smoking is a Risk Factor for Autoimmune Hepatitis: An English Registry-Based Case–Control Study

Clinical Epidemiology
Lisbet Grønbæk,1– 3 Harmony Omeife,3 Lu Ban,4 Colin J Crooks,5 Timothy R Card,3,4 Peter Jepsen,1,3 Joe West3,4,6 1Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark; 2Department of Medicine, Regional Hospital ...
Grønbæk L, Omeife H, Ban L, Crooks CJ, Card TR, Jepsen P, West J   +6 more
doaj  

Success of transition to adult care in patients with pediatric‐onset chronic liver disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Previous studies on chronic pediatric‐onset conditions have highlighted the risks of loss to follow‐up, disease progression, or therapeutic nonadherence during transition. However, very few studies have focused on liver diseases.
Sarah Mongbo, Valérie Canva, Sébastien Dharancy, Guillaume Lassailly, Alexandre Louvet, Philippe Mathurin, Nassima Ramdane, Frédéric Gottrand, Madeleine Aumar   +8 more
wiley   +1 more source

Clinical spectrum and outcomes of autoimmune hepatitis in children: a quaternary centre experience

Journal of the Pakistan Medical Association
Objectives: To analyse paediatric autoimmune hepatitis with respect to disease severity, treatment response, and clinical outcomes, including progression to liver failure and transplant survival.
Nazia Iqbal, Iqtadar Seerat, Sobia Noureen, Hassan Bashir   +3 more
doaj   +1 more source

ESPGHAN position paper on screening, diagnosis and investigation of paediatric metabolic dysfunction‐associated steatotic liver disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common reason for elevated liver enzymes in children in Europe, affecting more than 5% of all children. Since the last iteration of this position paper, there have been substantial advances in our understanding of the disease.
Jake P. Mann, Sander Lefere, Maarten Buytaert, Anna Alisi, Cigdem Arikan, Jernej Brecelj, Rachel M. Brown, Irene Degrassi, Giulia Fiore, Emer Fitzpatrick, Sven Francque, Christian A. Hudert, Wojciech Janczyk, Lauren Johansen, Bart G. Koot, Anastasia Konidari, Eberhard Lurz, Claudia Mandato, Maria Mercadal‐Hally, Hadar Moran‐Lev, Antonella Mosca, Giusy Ranucci, Maria Rogalidou, Penelope C. Rose, Piotr Socha, Pietro Vajro, Elvira Verduci, Anita C. E. Vreugdenhil, Natalia Zavhorodnia, Aglaia Zellos, Ruth De Bruyne   +30 more
wiley   +1 more source