Results 81 to 90 of about 112,037 (251)

Clinical observations of giant cell hepatitis in children

Журнал инфектологии, 2019
Giant cell hepatitis is characterized, by inflammation and large multinucleated. hepatocytes in hepatic parenchyma It is an unusual hepatocytes response to various noxious stimuli, characterized, by presence of multinucleated cells in liver with ...
E. N. Sergienkci, O. N. Romanova, A. A. Klyuchareva, N. V. Klimovich, S. K. Kletskiy, I. V. Sakharov, T. I. Lisitskaya, A. M. Kashkan, M. D. Ocheretny, E. A. Buldyk, V. P. Grinchak, Yu. V. Strizhak   +11 more
doaj   +1 more source

Autoimmune hepatitis on the rise

Journal of Hepatology, 2014
1st Dept. of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, GermanySee Article, pages 612–617Autoimmune hepatitis (AIH) is considered a rare disease. Theincidence and prevalence of AIH has been assessed in only twostudies on a population based level [1,2].
Schramm, Christoph, Lohse, Ansgar W.
openaire   +2 more sources

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Hepatitis as the presenting symptom of childhood systemic lupus erythematosus

The Turkish Journal of Pediatrics, 1999
We report in this article a girl with an initial diagnosis of autoimmune hepatitis who developed full-blown systemic lupus erythematosus (SLE) at her two-years follow-up.
R A Apak, N Beşbaş, S Ozdemir, H Ozen, A Bakkaloğlu, U Saatçi   +5 more
doaj  

Management of refractory autoimmune hepatitis with rituximab: a case series

Journal of Medical Case Reports
Background and aims Most patients with autoimmune hepatitis respond to the standard of care of prednisolone in combination with a thiopurine, or a second line of mycophenolate mofetil or tacrolimus.
Nicholas M. Batt, Stephen D. Bloom, Geoffrey Haar, Amanda J. Nicoll   +3 more
doaj   +1 more source

Secondary Hemophagocytic Lymphohistiocytosis: A Challenging Diagnosis in a Patient with Autoimmune Hepatitis

Case Reports in Critical Care, 2019
Background. We describe a case of secondary Hemophagocytic Lymphohistiocytosis (HLH) from autoimmune hepatitis mimicking severe sepsis in a man admitted to the intensive care unit. Case Presentation.
Colin Casault, Juan G. Posadas-Calleja
doaj   +1 more source

Tolerability of Adjuvant Nivolumab in Esophageal or Gastroesophageal Junction Cancer: A Real‐World Study

International Journal of Cancer, EarlyView.
ABSTRACT Adjuvant nivolumab is approved for esophageal or gastroesophageal junction cancer after neoadjuvant chemoradiotherapy and resection. In the CheckMate‐577 trial, Grade 3–5 nivolumab‐related adverse events (AEs) occurred in 5% of patients, with early discontinuation due to toxicity in 9%. However, real‐world data on immunotherapy‐related adverse
Michelle Koops van ’t Jagt, Anniek Strijdhorst, Tamara Jessica Huizer, Esther Albertien Kleibeuker, Sarah Derks, Bianca Mostert, Hanneke van Laarhoven, Jacco Juri de Haan   +7 more
wiley   +1 more source

Diabetes Increases Immunotherapy‐Related Toxicity but Not Efficacy in Metastatic Non‐Small Cell Lung Cancer: A Multicenter Retrospective Study

International Journal of Cancer, EarlyView.
ABSTRACT This multicenter retrospective study evaluated the impact of type 2 diabetes mellitus (DM) on clinical outcomes and immune‐related adverse events (irAEs) in 450 patients with metastatic non‐small cell lung cancer (NSCLC) treated with second‐line nivolumab at 17 centers between 2016 and 2024. Among these patients, 118 (26.2%) had DM.
Emre Çakır, Didem Divriklioğlu, Deniz Can Güven, Gamze Serin Özel, Oğuzhan Yıldız, Gamze Emin, Merve Keskinkılıç, Yeşim Ağyol, Onur Yazdan Balçık, Nagihan Kolkıran, Hale Gülçin Yıldırım Doğan, Pervin Can Şancı, Özge Yalıcı, Teoman Şakalar, Yurdagül Danacı, Yakup Düzköprü, Canan Yıldız, Mesut Yılmaz, İlhan Hacıbekiroğlu, Bülent Erdoğan, Saadettin Kılıçkap, Gamze Gököz Doğu, Melek Karakurt Eryılmaz, Atila Yıldırım, İlhan Öztop, İbrahim Vedat Bayoğlu, Şahnura Uzuntaş, Atike Pınar Erdoğan, Emir Çelik, Devrim Çabuk, Erdoğan Selçuk Şeber, Zehra Sadak Öcal, Hacer Demir   +32 more
wiley   +1 more source

Infliximab-induced autoimmune-like hepatitis in a patient with Crohn’s disease: a case report

Future Science OA
As medical treatments advance, drug-induced liver injury (DILI) becomes more prevalent, occurring at a rate of 14 to 19 cases per 100,000 individuals. We present a unique case of a female patient with Crohn’s disease developing autoimmune-like hepatitis ...
Shema Ayadi, Salma Merhaben, Linda Hadj Kacem, Soumaya Rammeh, Asma Mensi, Emna Belhadj Mabrouk, Yosra Zaimi, Leila Mouelhi   +7 more
doaj   +1 more source

Incidence and Predictors of Immune‐Related Hypothyroidism Under Pembrolizumab Across Gynecologic Malignancies and Melanoma: A Real‐World Cohort Study

International Journal of Cancer, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) frequently cause thyroid immune‐related adverse events (irAEs). Permanent hypothyroidism, the clinically most relevant phenotype, requires lifelong hormone replacement. We investigated its incidence, course, risk factors, and prognostic relevance under pembrolizumab.
Freya Koffka, Johann Kornowski, Elena Laakmann, Barbara Schmalfeldt, Tim Zell, Glenn Geidel, Christoffer Gebhardt, Pia Roser, Volkmar Müller, Julian Kött   +9 more
wiley   +1 more source