Results 101 to 110 of about 941,634 (294)

Autoimmune Cholangitis: A Variant Syndrome of Autoimmune Hepatitis

Case Reports in Hepatology, 2014
Autoimmune cholangitis (AIC) or autoimmune cholangiopathy is a chronic inflammation of liver and a variant syndrome of autoimmune hepatitis (AIH). We present a case of an adult female who had biochemical features of cholestasis and transaminasemia but ...
Brij Sharma, Sujeet Raina, Rajesh Sharma
doaj   +1 more source

Liver homing of clinical grade Tregs after therapeutic infusion in patients with autoimmune hepatitis

JHEP Reports, 2019
Background & Aims Autoimmune hepatitis (AIH) is an immune-mediated disease with no curative treatment. Regulatory T cell (Treg) therapy is potentially curative in AIH given the critical role of Tregs in preventing autoimmunity.
Y. Oo, Susan Ackrill, Richard Cole, L. Jenkins, P. Anderson, H. Jeffery, Nicholas Jones, L. Jeffery, P. Lutz, R. Wawman, A. Athwal, Jacqui Thompson, Joanna Gray, K. Guo, D. Barton, G. Hirschfield, T. Wong, P. Guest, D. Adams   +18 more
semanticscholar   +1 more source

Recurrent and De Novo Autoimmune Hepatitis

Liver transplantation, 2019
Clinical indications for liver transplantation (LT) in patients with autoimmune hepatitis (AIH) are identical to those of patients with other chronic liver diseases that end in acute or semiacute liver failure, decompensated cirrhosis, or hepatocellular ...
G. Stirnimann, M. Ebadi, A. Czaja, A. Montano‐Loza   +3 more
semanticscholar   +1 more source

Aetiopathogenesis of autoimmune hepatitis

World Journal of Gastroenterology, 2008
The histological hallmark of autoimmune hepatitis (AIH) is a dense portal mononuclear cell infiltrate that invades the surrounding parenchyma and comprises T and B lymphocytes, macrophages, and plasma cells. An unknown but powerful stimulus must be promoting the formation of this massive inflammatory cellular reaction that is likely to initiate and ...
Vergani, D, Mieli-Vergani, G
openaire   +3 more sources

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Target Proteins in Human Autoimmunity: Cytochromes P450 and Udp-Glycoronosyltransferases

Canadian Journal of Gastroenterology, 2000
Cytochromes P450 (CYPs) and UDP-glucuronosyltransferases (UGTs) are targets of autoantibodies in several hepatic and extrahepatic autoimmune diseases.
Petra Obermayer-Straub, Christian Peer Strassburg, Michael Peter Manns   +2 more
doaj   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Seronegative Autoimmune Hepatitis A Clinically Challenging Difficult Diagnosis

Case Reports in Medicine, 2017
Autoimmune hepatitis (AIH) is a complex liver disease of unknown cause which results in immune-mediated liver injury with varied clinical presentations.
Jagannath M. Sherigar, Arefiev Yavgeniy, Debra Guss, Nhu Ngo, Smruti Mohanty   +4 more
doaj   +1 more source

Autoimmune hepatitis in children

Jornal de Pediatria, 2000
Autoimmune hepatitis (AIH) is a disease of unknown aetiology, in which a progressive destruction of the hepatic parenchyma occurs. This disease follows a chronic, but fluctuating course. AIH spontaneously progresses towards cirrhosis and liver failure, but often shows a relatively good response to immunosuppressive treatment1.
openaire   +3 more sources

Autoimmune hepatitis and IgG4-related disease

World Journal of Gastroenterology, 2019
IgG4-related disease (IgG4-RD) is a chronic-fibroinflammatory disorder affecting a wide range of organs. Elevation of serum IgG4 concentrations and abundant infiltration of IgG4-expressing plasma cells are key diagnostic features of this autoimmune ...
Kosuke Minaga, Tomohiro Watanabe, Hobyung Chung, M. Kudo   +3 more
semanticscholar   +1 more source