Results 221 to 230 of about 112,037 (251)
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Digestion, 2009
A previously well young woman presented with an acute hepatitis resembling viral hepatitis and a liver biopsy after 5 weeks showed features of acute hepatitis. Infection with identifiable viruses or other organisms known to cause hepatitis was excluded. Evidence for autoimmune chronic active hepatitis ab initio included prolonged fever, lymphadenopathy,
Crapper, RM +3 more
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A previously well young woman presented with an acute hepatitis resembling viral hepatitis and a liver biopsy after 5 weeks showed features of acute hepatitis. Infection with identifiable viruses or other organisms known to cause hepatitis was excluded. Evidence for autoimmune chronic active hepatitis ab initio included prolonged fever, lymphadenopathy,
Crapper, RM +3 more
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Autoimmune hepatitis in childhood
Hepatology Research, 2007Autoimmune hepatitis (AIH) is a generally progressive inflammatory liver disease of unknown etiology that occurs in adults and children. Although the peak age of incidence is in prepubertal girls, AIH has been diagnosed as early 6 months of age. Two types of AIH are recognized according to the nature of the autoantibody detected in children at the time
Tomoo, Fujisawa +3 more
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Pregnancy with autoimmune hepatitis.
Gastroenterology and hepatology from bed to bench, 2016The aim of this study was to review our experience with gestations in autoimmune hepatitis patients.There are only limited data describing pregnancy in patients with autoimmune hepatitis.Retrospective analysis of pregnancies with autoimmune hepatitis followed in Centro Hospitalar do Porto, Portugal in the last ten years.We reported nine pregnancies in ...
Braga, António +2 more
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Mechanisms of autoimmune hepatitis
Current Opinion in Gastroenterology, 2020Purpose of review Autoimmune hepatitis (AIH) is a chronic disease characterized by a lymphocyte infiltrate in the liver. For decades, nonspecific immunosuppression has been used to limit chronic liver inflammation. The high risk of relapse, the treatments side effects, and the significant number of refractory patients are the ...
Cardon, Anaïs +2 more
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Autoimmune Hepatitis in the Elderly
American Journal of Gastroenterology, 2001Autoimmune hepatitis (AIH) is widely believed to be a disease of young women and menopause. Little is known about the frequency and clinical characteristics in patients aged > or =65 yr.We reviewed charts of 120 consecutive outpatients with known AIH to identify patients who were diagnosed at the age of 65 or older. These 20 patients (median age, 69 yr)
C, Schramm +4 more
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Pathogenesis of autoimmune hepatitis
Clinics in Liver Disease, 2002Autoimmune hepatitis is initiated by CD4 T cells that recognize self-antigen. The effector cells differentiate into functional phenotypes according to cytokines in the microenvironment and the nature of the triggering antigen. Hepatocytes can express class II molecules and present antigenic peptides through a bystander mechanism.
Vergani, D +3 more
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Pathogenesis of autoimmune hepatitis
Best Practice & Research Clinical Gastroenterology, 2011The mechanisms underlying the pathogenesis of autoimmune hepatitis are not fully understood, though there is growing evidence that genetic predisposition, molecular mimicry and/or impairment of regulatory T-cells are involved in the initiation and perpetuation of the autoimmune liver attack.
Liberal, Rodrigo +3 more
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Best Practice & Research Clinical Gastroenterology, 2003
M P, Manns, C P, Strassburg
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M P, Manns, C P, Strassburg
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Transplantation for Autoimmune Hepatitis
Seminars in Liver Disease, 2002Autoimmune hepatitis (AIH) is a good indication for liver transplantation, with 5- and 10-year survival rates approaching 75%. Determining the timing for transplantation remains difficult because progression to end-stage disease may be difficult to predict. After transplantation, the patients are at risk of recurrent AIH.
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