Results 211 to 220 of about 941,634 (294)

Stability and Variability of Symptom Burden in Primary Biliary Cholangitis: Insights From a Decade of Follow‐Up

Hepatology Research, EarlyView.
Impairment of health‐related quality of life in patients with PBC, in particular observed in younger female, represents distinct dimensions of disease impact, independently of long‐term outcomes. Overall and interindividual changes in PBC‐40 scores greatly varied over 10 years, suggesting that symptom burdens are driven by heterogeneous underlying ...
Akihito Takeuchi, Atsumasa Komori, Kazuhito Kawata, Osamu Yoshida, Kazunari Tanaka, Kazumichi Abe, Yukihisa Fujinaga, Tadashi Namisaki, Naruhiro Kimura, Tomohiro Katsumi, Ryo Miura, Naoko Tachizawa, Yoshinari Asaoka, Yoshiyuki Ueno, Shuji Terai, Hiromasa Ohira, Hitoshi Yoshiji, Kentaro Kikuchi, Takeshi Matsui, Tadashi Ikegami, Akira Honda, Masanori Abe, Atsushi Tanaka   +22 more
wiley   +1 more source

Overlap Syndrome Between Autoimmune Hepatitis and Primary Sclerosing Cholangitis in a Seven-Year-Old Child: A Case Report. [PDF]

Cureus
Cherrabi C, Hamami A, Babakhouya A, Kamaoui I, Rkain M.   +4 more
europepmc   +1 more source

Histological AI‐Assisted Analysis Outperforms Pathologist Assessment in Predicting Disease Outcomes in PSC Patients

Hepatology Research, EarlyView.
Analyzing liver histology with AI assistance demonstrates superior prognostic performance compared to manual scoring in PSC. AI‐measured portal inflammation, fibrosis, biliary epithelium, and blood vessels predicted key clinical endpoints, such as liver transplantation due to end‐stage liver disease, highlighting the importance of liver histology as a ...
Anna M. Salonen, Iiris Nyholm, Linn Tähti, Matilda Sinkko, Darshan Kumar, Martti Färkkilä, Johanna Arola, Mikko P. Pakarinen, Sonja Boyd, Nelli Sjöblom   +9 more
wiley   +1 more source

Efavirenz-Induced Hepatitis Mimicking Autoimmune Hepatitis: A Case Report. [PDF]

Cureus
Chowdhury AH, Chowdhury D, Jahan I, Woghiren A, Saleh M.   +4 more
europepmc   +1 more source

Serum Agalactosyl IgG Predicts Hepatocellular Carcinoma and All‐Cause Mortality After SVR in Advanced Chronic Hepatitis C

Hepatology Research, EarlyView.
ABSTRACT Background and Aims Patients with chronic hepatitis C and advanced fibrosis remain at substantial risk of hepatocellular carcinoma (HCC) and non‐liver–related death even after sustained virological response (SVR) to direct‐acting antivirals (DAA).
Daisuke Sakon, Jumpei Kondo, Yuki Tahata, Hayato Hikita, Maki Iwaisako, Muya Matsumoto, Asuka Ogata, Shinji Takamatsu, Yasutoshi Nozaki, Naruyasu Kakita, Hisashi Ishida, Fumihiko Nakanishi, Yuichi Yoshida, Masanori Nakahara, Kazuho Imanaka, Mitsuru Sakakibara, Takayuki Yakushijin, Tetsuo Takehara, Takahiro Kodama, Eiji Miyoshi   +19 more
wiley   +1 more source

Guillain-Barré Syndrome Mimicking Autoimmune Hepatitis: A Rare Entity. [PDF]

ACG Case Rep J
Abdelmotelib I, Rosario Lora D, Abdelhalim O, Abosheaishaa H, Eswaran S, Reau N.   +5 more
europepmc   +1 more source

Indoleamine 2,3‐Dioxygenase 1 as an Adjunctive Histopathological Marker of Cholangitis Activity in Primary Biliary Cholangitis

Hepatology Research, EarlyView.
IDO‐1 immunostaining identifies primary biliary cholangitis even in morphologically subtle bile duct lesions. IDO‐1 expression reflects cholangitis activity and is suppressed by ursodeoxycholic acid treatment, indicating its value as a dynamic diagnostic adjunct rather than a static marker of chronic damage.
Kaori Yoshimura, Shinji Shimoda, Ryoka Masuda, Tram Nguyen Thi, Rui Yang, Quynh Nguyen Thi, Dong Le Thanh, Yuko Tamano, Yasunori Sato, Taro Yamashita, Kenichi Harada   +10 more
wiley   +1 more source

Use of Machine Learning in Predicting the Risk of Cirrhosis in Autoimmune Hepatitis Based on Clinical and Immunological Indicators. [PDF]

Diagnostics (Basel)
Ashimova N, Raissova A, Kuantay E, Khozhakhmedova M, Aldabergenova N, Suleimenova M, Abzaliyev K, Nargiza N, Kulmanbetov R, Nersesov A.   +9 more
europepmc   +1 more source

Clinical Outcomes of Gradual Corticosteroid Tapering for Immune Checkpoint Inhibitor‐Induced Liver Injury

Hepatology Research, EarlyView.
Patients with severe ICI‐induced liver injury are commonly treated with corticosteroids, but the optimal tapering strategy remains uncertain. In this study, a gradual corticosteroid tapering strategy based partly on Japanese clinical practice for autoimmune hepatitis was associated with a low rate of relapse and enabled many patients to safely resume ...
Naoto Soma, Yoshihito Uchida, Kayoko Sugawara, Masamitsu Nakao, Nobuaki Nakayama, Yukinori Imai, Suguru Mizuno, Satoshi Mochida   +7 more
wiley   +1 more source

The Gut Microbiome as a Therapeutic Target in Alopecia Areata: Not Yet Part of the Patient Treatment Plan

International Journal of Dermatology, EarlyView.
ABSTRACT Interest in the gut microbiome as a therapeutic target for treating alopecia areata (AA) has grown considerably. However, existing evidence remains limited and inconsistent. Currently, there is insufficient evidence to recommend microbiome‐directed testing and therapies to patients with AA.
Eric McMullen, Deema Abdel Hafeez, Nikhil Pai, Laurence Mainville, Shireen Dumont, Narachai Julanon, Romy Shenderey, Grace Xiong, Shahnawaz Towheed, Jeffrey Donovan   +9 more
wiley   +1 more source