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Autoimmune hepatitis is an inflammatory liver disease in which the immune system is believed to orchestrate an immune attack onto the liver cell. Current knowledge suggests that both T helper 1 (TH1) and TH2 programmes are involved in the generation of the liver damage.
Edward L Krawitt, E L Krawitt
exaly +14 more sources
Autoimmune hepatitis was one of the first liver diseases for which an effective treatment was developed and the benefit proven by randomized controlled trials. Nonetheless, both the diagnosis and the treatment of autoimmune hepatitis remain full of challenges.
Diego Vergani
exaly +3 more sources
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Nature Reviews Disease Primers, 2018
Autoimmune hepatitis (AIH) is a severe liver disease that affects children and adults worldwide. The diagnosis of AIH relies on increased serum transaminase and immunoglobulin G levels, presence of autoantibodies and interface hepatitis on liver histology.
Diego Vergani, Aldo J Montano-Loza
exaly +7 more sources
Autoimmune hepatitis (AIH) is a severe liver disease that affects children and adults worldwide. The diagnosis of AIH relies on increased serum transaminase and immunoglobulin G levels, presence of autoantibodies and interface hepatitis on liver histology.
Diego Vergani, Aldo J Montano-Loza
exaly +7 more sources
Current Gastroenterology Reports, 2005
Autoimmune hepatitis (AIH) is a progressive inflammatory hepatitis of unknown etiology that is responsive to immunosuppressive therapy. The diagnosis of AIH should be guided by the descriptive criteria and scoring system set forth by the International Autoimmune Hepatitis Group.
Heike, Bantel +2 more
+7 more sources
Autoimmune hepatitis (AIH) is a progressive inflammatory hepatitis of unknown etiology that is responsive to immunosuppressive therapy. The diagnosis of AIH should be guided by the descriptive criteria and scoring system set forth by the International Autoimmune Hepatitis Group.
Heike, Bantel +2 more
+7 more sources
Journal of Pediatric Gastroenterology and Nutrition, 2009
ABSTRACTAutoimmune hepatitis is characterized by inflammatory liver histology, circulating nonorgan‐specific autoantibodies, and increased levels of immunoglobulin G, in the absence of a known etiology. Two types of juvenile autoimmune hepatitis (AIH) are recognized according to seropositivity for smooth muscle and/or anti‐nuclear antibody (AIH type 1)
Mieli-Vergani, Giorgina +10 more
openaire +4 more sources
ABSTRACTAutoimmune hepatitis is characterized by inflammatory liver histology, circulating nonorgan‐specific autoantibodies, and increased levels of immunoglobulin G, in the absence of a known etiology. Two types of juvenile autoimmune hepatitis (AIH) are recognized according to seropositivity for smooth muscle and/or anti‐nuclear antibody (AIH type 1)
Mieli-Vergani, Giorgina +10 more
openaire +4 more sources
Surgical Pathology Clinics, 2013
Autoimmune hepatitis is a chronic necroinflammatory disease of unknown etiology that is characterized by increased aminotransferases, serum autoantibodies, increased immunoglobulin G levels, and histological interface hepatitis. The disease does not have a pathognomonic clinical, laboratory, or histological feature; diagnosis depends on a combination ...
Cristina D, Cole, Romil, Saxena
openaire +5 more sources
Autoimmune hepatitis is a chronic necroinflammatory disease of unknown etiology that is characterized by increased aminotransferases, serum autoantibodies, increased immunoglobulin G levels, and histological interface hepatitis. The disease does not have a pathognomonic clinical, laboratory, or histological feature; diagnosis depends on a combination ...
Cristina D, Cole, Romil, Saxena
openaire +5 more sources
The Indian Journal of Pediatrics, 2001
Autoimmune hepatitis is one of the causes of chronic progressive liver disease in childhood. Here we report 14 cases with clinical findings, therapeutic management and prognosis, in order to define the course of the disease. Diagnosis of autoimmune hepatitis was done with the presence of at least one of these autoantibodies; antinuclear antibody ...
ÖZEN, HASAN +4 more
openaire +3 more sources
Autoimmune hepatitis is one of the causes of chronic progressive liver disease in childhood. Here we report 14 cases with clinical findings, therapeutic management and prognosis, in order to define the course of the disease. Diagnosis of autoimmune hepatitis was done with the presence of at least one of these autoantibodies; antinuclear antibody ...
ÖZEN, HASAN +4 more
openaire +3 more sources
Orvosi Hetilap, 2007
First the short history of the disease, then its etiopathogenesis, the role of genetic, environmental and immunologic factors are described. In the second part, the questions of diagnosis, differential diagnosis and the immunosuppressive treatment, with new therapeutic modalities and liver transplantation are discussed.
openaire +3 more sources
First the short history of the disease, then its etiopathogenesis, the role of genetic, environmental and immunologic factors are described. In the second part, the questions of diagnosis, differential diagnosis and the immunosuppressive treatment, with new therapeutic modalities and liver transplantation are discussed.
openaire +3 more sources
The Indian Journal of Pediatrics, 1995
Autoimmune hepatitis can present as either acute or chronic disease in children. Clinical and laboratory features, including association with extrahepatic autoimmune syndromes and prompt response to immunosuppressive treatment, circulating autoantibodies and hypergammaglobulinemia, suggest an immune etiology.
openaire +2 more sources
Autoimmune hepatitis can present as either acute or chronic disease in children. Clinical and laboratory features, including association with extrahepatic autoimmune syndromes and prompt response to immunosuppressive treatment, circulating autoantibodies and hypergammaglobulinemia, suggest an immune etiology.
openaire +2 more sources

