Advanced Science, EarlyView.Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon +8 more
wiley +1 more source
Discovery of Blood-Based Proteins That Mark Benzo[a]pyrene Modulation of Autoimmunity. [PDF]
Int J Mol SciKennicott K, Nie Y, Liang Y.
europepmc +1 more source
Retinoic Acid Reprograms Mast Cells Toward a Proinflammatory State to Enhance Antitumor Immunity
Advanced Science, EarlyView.Proinflammatory mast cells represent an MHC‐IIhigh, cytokine‐producing mast cell subset associated with improved survival and enhanced responses to anti‐PD‐1 therapy. Retinoic acid drives their polarization, enabling antigen uptake and presentation, and T cell recruitment and activation, collectively promoting adaptive anti‐tumor immunity.
Lizao Zhang +25 more
wiley +1 more source
Linking Thyroid Function, Morphology, Autoimmunity, Body Mass Index, and Reproductive Aging to Women's Sexual Health: Evidence from a Population Study in Kaunas. [PDF]
J Clin MedDaukšienė D +12 more
europepmc +1 more source
Advanced Science, EarlyView.HTGTS‐TCR‐seq is an efficient and cost‐effective method for profiling TCRα and TCRβ rearrangements using only a few primers. It captures both productive and nonproductive recombination events, minimizes primer bias, and reveals stage‐specific and age‐related repertoire changes in mice, as well as conserved features in human peripheral T cells ...
Rui Luo +9 more
wiley +1 more source
Association between anti-Mullerian hormone and antithyroid antibodies detectability and positivity in women assisted at a fertility clinic. [PDF]
JBRA Assist ReprodOliveira YIL +4 more
europepmc +1 more source
Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair
Advanced Science, EarlyView.This study maps mesenchymal stromal cells (MSCs) across multiple tissues, revealing that bone marrow–derived MSCs mobilize monocytes via CCL2 to promote systemic inflammation but do not migrate to distant organs to form fibrotic or tumor stroma. Instead, local MSCs dominate tissue remodeling, suggesting a “two‐hit” model linking systemic inflammation ...
Xinyu Thomas Tang +4 more
wiley +1 more source
Editorial: Community series in the role of monocytes/macrophages in autoimmunity and autoinflammation, volume II. [PDF]
Front ImmunolIwamoto N +3 more
europepmc +1 more source
Molecular genetics of common variable immunodeficiency
, 2017 Bogaert, Delfien +3 more
core +1 more source