Results 251 to 260 of about 349,570 (384)

Tryptophan Metabolite Indole‐3‐Aldehyde Induces AhR and c‐MYC Degradation to Promote Tumor Immunogenicity

Advanced Science, EarlyView.
Tryptophan metabolite Indole‐3‐aldehyde (I3A) downregulates cytosolic AhR and p‐ERK/c‐MYC proteins, together enhancing STAT3 phosphorylation and tumor immunogenicity. Overexpression of the Trp metabolic enzyme interleukin‐4‐induced gene‐1 (IL4I1) in tumor cells increases intracellular levels of I3A and enhances tumor immunogenicity.
Lei Cui, Zining Wang, Zixuan Guo, Hongxia Zhang, Yongxiang Liu, Huanling Zhang, Huan Jin, Feifei Xu, Xiaojuan Wang, Chunyuan Xie, Hui Guo, Tiantian Wang, Yanxun Lin, Qi Zhao, Penghui Zhou, Jing Tan, Jin‐Xin Bei, Peng Huang, Jinyun Liu, Xiaojun Xia   +19 more
wiley   +1 more source

Hashimoto's Thyroiditis and Female Fertility: Endocrine, Immune, and Microbiota Perspectives in Assisted Reproduction-A Narrative Review. [PDF]

Biomedicines
Popa EC, Maghiar L, Maghiar TA, Brihan I, Georgescu LM, Toderaș BA, Sachelarie L, Huniadi A.   +7 more
europepmc   +1 more source

The relationship of infection with Chlamydia trachomatis to the parameters of male fertility and sperm autoimmunity

, 1987
Clare E. Close, San Pin Wang, Pacita L. Roberts, Richard E. Berger   +3 more
openalex   +1 more source

Cross-reactive antigen recognition by an encephalitogenic T cell receptor. Implications for T cell biology and autoimmunity. [PDF]

, 1992
David C. Wraith, Brita Bruun, Paul J. Fairchild   +2 more
openalex   +1 more source

Molecular mimicry and autoimmunity.

Journal of Autoimmunity, 2018
M. Rojas, Paula Restrepo-Jiménez, D. Monsalve, Y. Pacheco, Y. Acosta-Ampudia, C. Ramírez-Santana, P. Leung, A. Ansari, M. Gershwin, J. Anaya   +9 more
semanticscholar   +1 more source

Engineered RGD‐Treg‐Exos Targeted Delivery of miR‐218‐5p to Activate Mitophagy and Attenuate Podocyte Injury in Diabetic Kidney Disease

Advanced Science, EarlyView.
Tregs‐Exos deliver miR‐218‐5p to increase mitophagy in podocytes by inhibiting the TNC/TLR4/SRC/FUNDC1 pathway. RGD‐Treg‐Exos, engineered to express RGD peptides on the membrane surface, bind to integrins on the surface of podocytes and effectively target podocytes for the delivery of miR‐218‐5p, which increases mitophagy and reduces apoptosis in ...
Zhaochen Guo, Shaohui Gao, Ziyue Wang, Zige Chen, Jinglei Chen, Aiping Duan, Feng Xu, Qinger Wang, Weisong Qin, Caihong Zeng, Zhihong Liu, Hao Bao   +11 more
wiley   +1 more source

Monkeypox virus and type 1 diabetes: a molecular insight into inflammatory signaling and β-cell autoimmunity. [PDF]

Virol J
Almutawif YA, Al-Kuraishy HM, Al-Gareeb AI, Albuhadily AK, Eid HMA, Alexiou A, Papadakis M, Abo-El Fetoh ME, El-Saber Batiha G.   +8 more
europepmc   +1 more source

Virus-induced autoimmunity: Molecular mimicry as a route to autoimmune disease

, 1989
Michael B. A. Oldstone
openalex   +1 more source

Oral iron chelator L1 and autoimmunity [letter; comment] [PDF]

, 1993
Minesh P. Mehta, Surinder Singhal, Mehta Bc   +2 more
openalex   +1 more source

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer

Nature, 2018
Shane J.F. Cronin, Corey R. Seehus, A. Weidinger, S. Talbot, S. Reissig, M. Seifert, Y. Pierson, E. McNeill, M. Longhi, B. L. Turnes, Taras Kreslavsky, Melanie Kogler, David Hoffmann, Melita Ticevic, D. Scheffer, L. Tortola, Domagoj Cikes, A. Jais, Manu Rangachari, Shuan Rao, Magdalena Paolino, M. Novatchkova, Martin Aichinger, L. Barrett, Alban Latremoliere, Gerald Wirnsberger, Guenther Lametschwandtner, M. Busslinger, S. Zicha, A. Latini, S. Robson, A. Waisman, Nick A. Andrews, M. Costigan, K. Channon, G. Weiss, A. Kozlov, M. Tebbe, K. Johnsson, C. Woolf, J. Penninger   +40 more
semanticscholar   +1 more source