Results 251 to 260 of about 339,261 (412)

Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity

open access: yesScience, 2013
J. Markle   +9 more
semanticscholar   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

open access: yesAdvanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang   +9 more
wiley   +1 more source

Autoimmunity induced by type II collagen-coupled spleen cells. [PDF]

open access: bronze, 1981
Robert T. Schoen   +5 more
openalex   +1 more source

Microneedle Patch for In Situ Neutrophil Monitoring

open access: yesAdvanced Science, EarlyView.
An in situ chromogenic microneedle patch that achieves daily blood neutrophil monitoring without vascular invasion or laboratory apparatus is developed. The detection ability is well demonstrated in a chemotherapy‐induced neutropenic rat model and can be read out using a mobile phone application.
Ziyi Lu   +26 more
wiley   +1 more source

Effect of 89Sr on immunity and autoimmunity in NZB/NZW F1 mice. [PDF]

open access: bronze, 1980
William E. Seaman   +3 more
openalex   +1 more source

Type 1 Diabetes Mellitus and Vitamin D. [PDF]

open access: yesInt J Mol Sci
Durá-Travé T, Gallinas-Victoriano F.
europepmc   +1 more source

Enhancing the Protein Stability of an Anticancer VHH‐Fc Heavy Chain Antibody through Computational Modeling and Variant Design

open access: yesAdvanced Science, EarlyView.
In this study, a computational pipeline is developed to systematically evaluate the conformational stability, disulfide bond reduction state, and aggregation and degradation tendencies of an anticancer VHH‐Fc fusion antibody. Based on the mechanistic insights, antibody variants with enhanced stability and increased yield are successfully designed. This
Yuan Fang   +10 more
wiley   +1 more source

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