Results 251 to 260 of about 296,707 (334)

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

Advanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera, Suneesh Thilak, Asha Patel, Prashant Nasa, Zubair Ahmed, Lorraine Jacques, William J. Scotton, Cyril Chacko, Randeep Mullhi, Ruoling Chen, Vikram Patil, Suresh Renukappa, Tonny Veenith   +12 more
wiley   +1 more source

Editorial: Exploring autoimmune diseases and endocrine crosstalk. [PDF]

Front Immunol
Wolff ASB, Antonelli A.
europepmc   +1 more source

Tacrolimus (FK506) and therapy of human autoimmune disorders [PDF]

, 1996
Abu-Elmagd, K, Carroll, PB, Irish, W, McCauley, J, McMichael, J, Rilo, HR, Starzl, TE, Thomson, AW, Van Thiel, DH   +8 more
core  

Autoimmunity in Autologous Islet Transplantation

, 2018
Khawla F. Ali, Vicente T. San Martin, Tyler Stevens, R. Matthew Walsh, Rita Bottino, Massimo Trucco, Betül Hatipoğlu   +6 more
openalex   +2 more sources

Stress‐Induced Activation of Prolactin‐NR4A1‐Midkine Axis Exacerbates Skin Inflammation

Advanced Science, EarlyView.
Chronic psychological stress activates prolactin signaling to reprogram dermal fibroblasts into APCDD1+ inflammatory effectors via NR4A1, driving midkine secretion. This paracrine hub amplifies keratinocyte proliferation and immune recruitment, thus exacerbating skin inflammation.
Zhiguo Li, Huiyi Quan, Wanting Liu, Jiaoling Chen, Mengyang Chu, Xin Tang, Ke Xue, Xuan Liu, Jingyi Ma, Yaxing Bai, Ruina Dong, Bing Li, Junfeng Hao, Wei Guo, Qingyang Li, Erle Dang, Johann E Gudjonsson, Gang Wang, Shuai Shao   +18 more
wiley   +1 more source

The role of microRNAs and long non-coding RNAs in epigenetic regulation of T cells: implications for autoimmunity. [PDF]

Front Immunol
Prasad S, Adivikolanu H, Banerjee A, Mittal M, Lemos JRN, Mittal R, Hirani K.   +6 more
europepmc   +1 more source

Autoimmunity and epilepsy in children

, 2013
A Berio, G Mangiante, A Piazzi
openalex   +2 more sources

Intrinsic MicroRNA‐10a Restricts Regulatory T Cell Suppressive Function and Intestinal Repair by Coordinating Transcriptional, Metabolic, and Epithelial Repair Pathways

Advanced Science, EarlyView.
This study identifies microRNA‐10a (miR‐10a) as a key brake on regulatory T cell (Treg) suppressive function and intestinal repair. By targeting Blimp‐1, Uqcrq, and amphiregulin, miR‐10a restrains transcriptional, metabolic, and epithelial programs essential for Treg activity.
Wenjing Yang, Tianming Yu, Hui Yang, Suxia Yao, Ruihua Ma, Elizabeth M Steinert, Karen M Ridge, Weiguo Cui, Navdeep S Chandel, Yingzi Cong   +9 more
wiley   +1 more source

Adult thymectomy is associated with increased mortality risk from cancer but not cardiovascular disease. [PDF]

Blood Adv
Kooshesh KA, Foy BH, Baylis RA, Gustafsson K, Zlotoff DA, Neilan TG, Scadden DT.   +6 more
europepmc   +1 more source