Results 271 to 280 of about 349,570 (384)

Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 mice. [PDF]

open access: bronze, 1994
Hiroshi Ishida   +5 more
openalex   +1 more source

Integrated Transcriptome and Metabolomics Analyses Show MYC as a Potential Therapeutic Target for Behçet's Uveitis

open access: yesAdvanced Science, EarlyView.
Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li   +11 more
wiley   +1 more source

Irisin Attenuates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension via Ubiquitin‐Mediated Regulation of ENO1

open access: yesAdvanced Science, EarlyView.
Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun   +15 more
wiley   +1 more source

Single-cell transcriptional landscape of peripheral myeloid cells in autoimmune diseases. [PDF]

open access: yesiScience
Wang FQ   +7 more
europepmc   +1 more source

Thyrotropin and growth promoting immunoglobulin (TGI) of FRTL-5 cells have no growth stimulating activity on human thyroid epithelial cell cultures [PDF]

open access: yes, 1987
Bay, V.   +9 more
core  

Cellular autoimmunity to retinal specific antigens in patients with Behcet's disease. [PDF]

open access: bronze, 1993
Joyce Hisae Yamamoto   +4 more
openalex   +1 more source

Identifying Myeloid‐Derived Suppressor Cells and Lipocalin‐2 as Therapeutic Targets for Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
Inflammatory dysregulation drives intervertebral disc degeneration via stage‐dependent immune cellular dynamics. Single‐cell transcriptomics and genetic risk mapping revealed a shift from LCN2high myeloid‐derived suppressor cells maintaining disc repair in early stages to IL1B+ macrophage‐dominated pathology in advanced disease.
Changmeng Zhang   +6 more
wiley   +1 more source

Hashimoto's Thyroiditis and Female Infertility: A Clinical and Statistical Investigation of Endocrine and Ovarian Markers. [PDF]

open access: yesJ Clin Med
Popa EC   +8 more
europepmc   +1 more source

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