Results 61 to 70 of about 153,226 (196)

Antagonizing Retinoic Acid-Related-Orphan Receptor Gamma Activity Blocks the T Helper 17/Interleukin-17 Pathway Leading to Attenuated Pro-inflammatory Human Keratinocyte and Skin Responses

Frontiers in Immunology, 2019
The nuclear hormone receptor retinoic acid receptor-related-orphan-receptor-gamma t (RORγt) is the key transcription factor required for Th17 cell differentiation and for production of IL-17 family cytokines by innate and adaptive immune cells ...
Florence Ecoeur, Jessica Weiss, Klemens Kaupmann, Samuel Hintermann, David Orain, Christine Guntermann   +5 more
doaj   +1 more source

Autoimmunity in Iron-deficiency Anaemia [PDF]

, 1964
Bart Moulton
openalex   +1 more source

The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity

Nature Communications, 2017
Excessive expansion of the T follicular helper (TFH) cell pool is associated with autoimmune disease and Def6 has been identified as an SLE risk variant.
Woelsung Yi, Sanjay Gupta, Edd Ricker, Michela Manni, Rolf Jessberger, Yurii Chinenov, Henrik Molina, Alessandra B. Pernis   +7 more
doaj   +1 more source

Administration of an AAV vector coding for a P2X7-blocking nanobody-based biologic ameliorates colitis in mice

Journal of Nanobiotechnology
Background The pro-inflammatory ATP-gated P2X7 receptor is widely expressed by immune and non-immune cells. Nanobodies targeting P2X7, with potentiating or antagonistic effects, have been developed.
Catalina Abad, Mélanie Demeules, Charlotte Guillou, Henri Gondé, Rachid Zoubairi, Yossan-Var Tan, Carolina Pinto-Espinoza, Waldemar Schäfer, Anna Marei Mann, Valérie Vouret-Craviari, Friedrich Koch-Nolte, Sahil Adriouch   +11 more
doaj   +1 more source

Autoimmunity in Lung Disease [PDF]

, 1965
Maxwell Caplin, L.H. Capel, William Wheeler   +2 more
openalex   +1 more source

Differential memory enrichment of cytotoxic CD4 T cells in Parkinson’s disease patients reactive to α-synuclein

npj Parkinson's Disease
Parkinson’s disease (PD) is a complex neurodegenerative disease with a largely unknown etiology. Although the loss of dopaminergic neurons in the substantia nigra pars compacta is the pathological hallmark of PD, neuroinflammation also plays a ...
Antoine Freuchet, Emil Johansson, April Frazier, Irene Litvan, Jennifer G. Goldman, Roy N. Alcalay, David Sulzer, Cecilia S. Lindestam Arlehamn, Alessandro Sette   +8 more
doaj   +1 more source

Autoimmunity in Diseases of the Thyroid, Adrenals and Gonads in Man [PDF]

, 1975
Elizabeth A. Calder, W.J. Penhale, W J Irvine   +2 more
openalex   +1 more source

Association of defective feedback suppressor t cell activity with autoimmunity in nzb mice [PDF]

, 1978
Richard K. Gershon, Diane D. Eardley, Kenneth F. Naidorf, Harvey Cantor   +3 more
openalex   +1 more source

Genetic studies of autoimmunity and retrovirus expression in crosses of New Zealand black mice I. Xenotropic virus. [PDF]

, 1978
Somnath Datta, Noga Manny, Chester Andrzejewski, J André-Schwartz, Robert S. Schwartz   +4 more
openalex   +1 more source

Autoimmunity. Clinical and Experimental

, 1968
L. E. Glynn
openalex   +1 more source