A Simple Biosensor-Based Assay for Quantitative Autoinducer-2 Analysis [PDF]
Bacteria produce and react to interspecies signaling molecules in order to control the expression of genes that are particularly beneficial when they are expressed by a bacterial community. In addition to intraspecies communication, the signaling molecule autoinducer-2 (AI-2) can also serve for interspecies communication between Gram-positive and Gram ...
Marla Keizers +2 more
openaire +2 more sources
Roles of autoinducer-2 mediated quorum sensing in wastewater treatment
Quorum sensing (QS) is considered to be a promising regulation method for biological wastewater treatment (WWT) due to its regulation in extracellular substances (EPS) production, biofilm formation, granulation, colonization and bacterial activity and ...
Yirong Liu, Huizhi Hu, Feng Luo
doaj +1 more source
LuxS influencesEscherichia colibiofilm formation through autoinducer-2-dependent and autoinducer-2-independent modalities [PDF]
Escherichia coli produces biofilms in response to the small molecule autoinducer-2 (AI-2), a product of the LuxS enzyme. LuxS is part of the activated methyl cycle and could also affect biofilm development by AI-2-independent effects on metabolism. A luxS deletion mutant of E.
Chen, Niu +6 more
openaire +2 more sources
Design, Synthesis, and Evaluation of Transition-State Analogs as Inhibitors of the Bacterial Quorum Sensing Autoinducer Synthase CepI [PDF]
Quorum sensing is a bacterial signaling system that involves the synthesis and detection of small signal molecules called autoinducers. A main class of autoinducers in Gram-negative bacteria are acylated homoserine lactones, produced by the LuxI family ...
Alec, Esposito +7 more
core +1 more source
Identification of Functional LsrB-Like Autoinducer-2 Receptors [PDF]
ABSTRACTAlthough a variety of bacterial species have been reported to use the interspecies communication signal autoinducer-2 (AI-2) to regulate multiple behaviors, the molecular mechanisms of AI-2 recognition and signal transduction remain poorly understood.
Pereira, C. S. +4 more
openaire +4 more sources
The Janthinobacterium sp. HH01 genome encodes a homologue of the V. cholerae CqsA and L. pneumophila LqsA autoinducer synthases. [PDF]
Janthinobacteria commonly form biofilms on eukaryotic hosts and are known to synthesize antibacterial and antifungal compounds. Janthinobacterium sp. HH01 was recently isolated from an aquatic environment and its genome sequence was established.
Blokesch, Melanie +86 more
core +1 more source
alpha-Hydroxyketone Synthesis and Sensing by Legionella and Vibrio [PDF]
Bacteria synthesize and sense low molecular weight signaling molecules, termed autoinducers, to measure their population density and community complexity. One class of autoinducers, the α-hydroxyketones (AHKs), is produced and detected by the water-borne
Hubert Hilbi +3 more
core +1 more source
As a universal quorum sensing (QS) signal, autoinducer-2 (AI-2) is utilized by both Gram-negative and Gram-positive bacteria to coordinate several group behaviors, such as biofilm formation, virulence, and motility, when the bacterial cell density ...
Kibaek Lee, Chung-Hak Lee, Kwang-Ho Choo
doaj +1 more source
Quorum sensing signaling molecules produced by reference and emerging soft-rot bacteria (Dickeya and Pectobacterium spp.). [PDF]
BackgroundSeveral small diffusible molecules are involved in bacterial quorum sensing and virulence. The production of autoinducers-1 and -2, quinolone, indole and γ-amino butyrate signaling molecules was investigated in a set of soft-rot bacteria ...
Alexandre Crépin +13 more
doaj +1 more source
Analysis of autoinducer-2 quorum sensing in Yersinia pestis. [PDF]
ABSTRACT The autoinducer-2 (AI-2) quorum-sensing system has been linked to diverse phenotypes and regulatory changes in pathogenic bacteria. In the present study, we performed a molecular and biochemical characterization of the AI-2 system in Yersinia pestis , the causative agent of plague. In strain CO92,
Yu J +7 more
europepmc +4 more sources

