Pomegranate extract affects fungal biofilm production: consumption of phenolic compounds and alteration of fungal autoinducers release [PDF]
Candida albicans expresses numerous virulence factors that contribute to pathogenesis, including its dimorphic transition and even biofilm formation, through the release of specific quorum sensing molecules, such as the autoinducers (AI) tyrosol and ...
Tagliazucchi D +8 more
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The Autoinducer-2 Exporter Superfamily [PDF]
The TqsA (YdgG) protein of <i>Escherichia coli</i> has been shown to export the autoinducer-2 (AI-2) molecule, a furanosyl borate diester that bears little resemblance to previously characterized biological molecules. TqsA belongs to a large superfamily, the AI-2 exporter (AI-2E) superfamily, of putative transporters with no other ...
Rettner, Rachael E, Saier, Milton H
openaire +4 more sources
Attenuation of Pseudomonas aeruginosa Virulence by Pomegranate Peel Extract
Pseudomonas aeruginosa is an opportunistic pathogen often responsible for biofilm-associated infections. The high adhesion of bacterial cells onto biotic/abiotic surfaces is followed by production of an extracellular polysaccharidic matrix and formation ...
Samuele Peppoloni +6 more
doaj +1 more source
Quorum Sensing Interfering Strategies and Their Implications in the Management of Biofilm-Associated Bacterial Infections [PDF]
The bacterial species employ various types of molecular communication systems recognized as quorum sensing for the synchronization of differential gene expression to regulate virulence traits and biofilm formation. A variety of quorum sensing inhibitors;
Samman Munir +8 more
doaj +1 more source
Quorum Sensing (QS) is a form of cell-to-cell communication that enables bacteria to modify behavior according to their population density. While QS has been proposed as a potential intervention against pathogen infection, QS-mediated communication ...
Jorge Peña-Díaz +6 more
doaj +1 more source
The Lantibiotic Mersacidin Is an Autoinducing Peptide [PDF]
ABSTRACT The lantibiotic (lanthionine-containing antibiotic) mersacidin is an antimicrobial peptide consisting of 20 amino acids and is produced by Bacillus sp. strain HIL Y-85,54728. The structural gene ( mrsA ) and the genes for producer self-protection, modification enzymes ...
Stephanie, Schmitz +4 more
openaire +2 more sources
Quorum sensing in Vibrio fischeri: probing autoinducer-LuxR interactions with autoinducer analogs [PDF]
The Vibrio fischeri luminescence genes are activated by the transcription factor LuxR in combination with a diffusible signal compound, N-(3-oxohexanoyl) homoserine lactone, termed the autoinducer. We have synthesized a set of autoinducer analogs. Many analogs with alterations in the acyl side chain showed evidence of binding to LuxR.
A L, Schaefer +3 more
openaire +2 more sources
Bacterial Quorum-Sensing Systems and Their Role in Intestinal Bacteria-Host Crosstalk
Quorum-sensing (QS) system is a rapidly developing field in which we are gradually expanding our understanding about how bacteria communicate with each other and regulate their activities in bacterial sociality.
Liang Wu, Yubin Luo
doaj +1 more source
In vitro regulation of quorum sensing in Pseudomonas aeruginosa using synthetic autoinducers By Hrag Dilabazian A thesis [PDF]
Quorum sensing is a remarkable type of cell-to-cell communication that is directly involved in the regulation of virulence, biofilm formation and other significant characteristics of bacteria.
Dilabazian, Hrag
core +1 more source
O objetivo deste trabalho foi caracterizar e agrupar rizobactérias, isoladas de hortaliças, quanto à morfologia cultural, riqueza e diversidade e avaliar a biossíntese de autoindutores N-acil lactonas homoserinas (ALH) e a capacidade de formação de ...
Rachel Pinton +6 more
doaj +1 more source

