Results 61 to 70 of about 8,137 (202)

Inflammatory and Immunological Basis of Periodontal Diseases

open access: yesJournal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima   +3 more
wiley   +1 more source

Mechanism of Vibrio cholerae Autoinducer-1 Biosynthesis

open access: yesACS Chemical Biology, 2011
Vibrio cholerae, the causative agent of the disease cholera, uses a cell to cell communication process called quorum sensing to control biofilm formation and virulence factor production. The major V. cholerae quorum-sensing signal CAI-1 has been identified as (S)-3-hydroxytridecan-4-one, and the CqsA protein is required for CAI-1 production.
Wei, Yunzhou   +4 more
openaire   +2 more sources

The lux autoinducer-receptor interaction in Vibrio harveyi: binding parameters and structural requirements for the autoinducer [PDF]

open access: yesBiochemical Journal, 1995
To assess the binding parameters and the structure-function relationship of the Vibrio harveyi lux autoinducer, N-(D-3-hydroxybutanoyl)homoserine lactone (D-HBHL), to light emission, a series of acylhomoserine lactone analogues were synthesized and their effects on the stimulation of luminescence of an autoinducer-deficient mutant of V.
J G, Cao, Z Y, Wei, E A, Meighen
openaire   +2 more sources

Spatial Dispersal of Bacterial Colonies Induces a Dynamical Transition From Local to Global Quorum Sensing

open access: yes, 2016
Bacteria communicate using external chemical signals called autoinducers (AI) in a process known as quorum sensing (QS). QS efficiency is reduced by both limitations of AI diffusion and potential interference from neighboring strains.
Boedicker, James Q., Yusufaly, Tahir I.
core   +1 more source

Synergistic Inhibitory Effect and Mechanism of Action of Cinnamaldehyde‐Carvacrol Nanoemulsion on the Staphylococcus aureus and Escherichia coli Mixed Biofilms Formation

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
The study prepared Cinnamaldehyde‐Carvacrol nanoemulsions (CA/CV NEs) through high‐energy emulsification. In a mouse infection model, CA/CV NEs exhibited a synergistic inhibitory effect on the formation of Staphylococcus aureus–Escherichia coli mixed biofilms, reducing PIA, LuxS/AI‐2, adhesion, athletic ability, and extracellular protein.
Siqi He   +4 more
wiley   +1 more source

Molecular radio jamming: autoinducer analogs.

open access: yesChemistry & biology, 2003
Synthesis of an N-acyl-homoserine lactone (N-acyl-HSL) analog library yields agonists and antagonists of the Pseudomonas aeruginosa quorum-sensing system. Active compounds also reveal heterogeneity in the lactone ring binding pockets of N-acyl-HSL-activated transcription factors.
openaire   +2 more sources

Strategies to prevent the occurrence of resistance against antibiotics by using advanced materials [PDF]

open access: yes, 2018
This is a post-peer-review, pre-copyedit version of an article published in Applied microbiology and biotechnology The final authenticated version is available online at: http://dx.doi.org/10.1007/s00253-018-8776-0Drug resistance occurrence is a global ...
Bassegoda Puigdomenech, Arnau   +3 more
core   +2 more sources

Asymmetric regulation of quorum-sensing receptors drives autoinducer-specific gene expression programs in Vibrio cholerae. [PDF]

open access: yesPLoS Genetics, 2017
Quorum sensing (QS) is a mechanism of chemical communication that bacteria use to monitor cell-population density and coordinate group behaviors. QS relies on the production, detection, and group-wide response to extracellular signal molecules called ...
Amanda Hurley, Bonnie L Bassler
doaj   +1 more source

Molecular Mechanisms of Algicidal Bacteria in Controlling Harmful Algal Blooms: Advances in Bacteria‐Algae Interactions

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 2, April 2026.
This review elucidates the molecular mechanisms of algicidal bacteria, highlighting critical behaviours like chemotaxis, quorum sensing and extracellular vesicle release. It details how these actions disrupt algal cellular integrity, photosynthesis and calcium homeostasis, providing a theoretical foundation for controlling harmful algal blooms ...
Jiaxin Wang, Binfu Xu, Lixing Huang
wiley   +1 more source

Quorum Sensing Autoinducer-3 Finally Yields to Structural Elucidation [PDF]

open access: yesACS Central Science, 2020
A novel quorum sensing autoinducer, which regulates virulence in enterohemorrhagic Escherichia coli, had eluded structural characterization—until now.
Delmis E. Hernandez, Herman O. Sintim
openaire   +2 more sources

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