Results 81 to 90 of about 5,157 (210)

Living Microbial Drugs

open access: yesChemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik   +3 more
wiley   +1 more source

N-acyl Homoserine Lactone-Producing Pseudomonas putida Strain T2-2 from Human Tongue Surface

open access: yesSensors, 2013
Bacterial cell-to-cell communication (quorum sensing) refers to the regulation of bacterial gene expression in response to changes in microbial population density.
Yeun Mun Choo   +5 more
doaj   +1 more source

Coumarins Disrupt Cell–Cell Communication and Virulence in Priority Pathogens: Targeting the PQS Signalling System in Pseudomonas aeruginosa

open access: yesMicrobial Biotechnology, Volume 19, Issue 7, July 2026.
The selective nature through which coumarin compounds produced by different species of plants target PQS signalling in Pseudomonas aeruginosa and select for distinct phenotypic responses in key pathogenic organisms adds to the growing evidence of their utility as natural virulence suppressors. ABSTRACT Cell‐to‐cell communication in microbial systems is
Dylan Boon   +8 more
wiley   +1 more source

Single cell analysis of Vibrio harveyi uncovers functional heterogeneity in response to quorum sensing signals

open access: yesBMC Microbiology, 2012
Background Vibrio harveyi and closely related species are important pathogens in aquaculture. A complex quorum sensing cascade involving three autoinducers controls bioluminescence and several genes encoding virulence factors. Single cell analysis of a V.
Anetzberger Claudia   +2 more
doaj   +1 more source

ThePseudomonas aeruginosaLasR quorum-sensing receptor balances ligand selectivity and sensitivity [PDF]

open access: yes, 2018
Quorum sensing is a cell-cell communication process that bacteria use to orchestrate group behaviors. Quorum sensing is mediated by extracellular signal molecules called autoinducers.
Bonnie L. Bassler   +3 more
core   +1 more source

An Experimentally Verified Mechanistic Model for Predicting Quorum Sensing‐Based Switches

open access: yesMicrobial Biotechnology, Volume 19, Issue 7, July 2026.
A predictive model was developed to fine‐tune EsaI/EsaR quorum sensing circuits, highlighting the transcription factor's pivotal role and offering a foundation for broader applications across LuxR‐family systems in synthetic biology. ABSTRACT Quorum sensing‐based genetic circuits are gaining traction in synthetic biology as they link population‐level ...
Jasmine De Baets   +2 more
wiley   +1 more source

Quorum sensing controls Vibrio cholerae multicellular aggregate formation

open access: yeseLife, 2018
Bacteria communicate and collectively regulate gene expression using a process called quorum sensing (QS). QS relies on group-wide responses to signal molecules called autoinducers.
Matthew Jemielita   +2 more
doaj   +1 more source

Azithromycin inhibits quorum sensing in Pseudomonas aeruginosa [PDF]

open access: yes, 2001
We report that 2 microg of azithromycin/ml inhibits the quorum-sensing circuitry of Pseudomonas aeruginosa strain PAO1. Addition of synthetic autoinducers partially restored the expression of the trancriptional activator-encoding genes lasR and rhlR but ...
Yamaguchi, K.   +5 more
core   +1 more source

Fungal‐Bacterial Interactions in Polymicrobial Infections: Hidden Threats

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
ABSTRACT Polymicrobial infections involving fungi and bacteria represent a major and increasingly recognized clinical challenge, in which interkingdom interactions significantly amplify disease severity, antimicrobial resistance, and treatment failure. Rather than passive co‐existence, fungal–bacterial communities form highly coordinated systems driven
Mohammad Javad Roustaye Gourabi   +3 more
wiley   +1 more source

A structural perspective on the mechanisms of quorum sensing activation in bacteria

open access: yesAnais da Academia Brasileira de Ciências, 2015
Bacteria are able to synchronize the population behavior in order to regulate gene expression through a cell-to-cell communication mechanism called quorum sensing.
CAROLINA LIXA   +3 more
doaj   +1 more source

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