Results 61 to 70 of about 8,210 (215)

The lux autoinducer-receptor interaction in Vibrio harveyi: binding parameters and structural requirements for the autoinducer [PDF]

Biochemical Journal, 1995
To assess the binding parameters and the structure-function relationship of the Vibrio harveyi lux autoinducer, N-(D-3-hydroxybutanoyl)homoserine lactone (D-HBHL), to light emission, a series of acylhomoserine lactone analogues were synthesized and their effects on the stimulation of luminescence of an autoinducer-deficient mutant of V.
J G, Cao, Z Y, Wei, E A, Meighen
openaire   +2 more sources

Phenazine‐Based Synthetic Biology to Signal Between Cells and Electrodes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Bioelectronic systems that enable seamless communication between electronic devices and living systems represent a transformative frontier in biotechnology. Among available methodologies, redox based signaling offers unique advantages due to its ubiquity in biology and compatibility with standard electrochemical equipment, expanding on ...
Eric VanArsdale, Monica Chu, Sally Wang, Divya Muthusamy, Eric Wold, Yi Liu, G. F. Payne, Tanya Tschirhart, W. E. Bentley   +8 more
wiley   +1 more source

Evaluation of a new high-throughput method for identifying quorum quenching bacteria [PDF]

, 2013
Quorum sensing (QS) is a population-dependent mechanism for bacteria to synchronize social behaviors such as secretion of virulence factors. The enzymatic interruption of QS, termed quorum quenching (QQ), has been suggested as a promising alternative ...
Bossier, Peter, Coenye, Tom, Shi, Xiaochong, Tang, Kaihao, Yu, Min, Zhang, Xiao-Hua, Zhang, Yunhui   +6 more
core   +2 more sources

Molecular radio jamming: autoinducer analogs.

Chemistry & biology, 2003
Synthesis of an N-acyl-homoserine lactone (N-acyl-HSL) analog library yields agonists and antagonists of the Pseudomonas aeruginosa quorum-sensing system. Active compounds also reveal heterogeneity in the lactone ring binding pockets of N-acyl-HSL-activated transcription factors.
openaire   +2 more sources

Asymmetric regulation of quorum-sensing receptors drives autoinducer-specific gene expression programs in Vibrio cholerae. [PDF]

PLoS Genetics, 2017
Quorum sensing (QS) is a mechanism of chemical communication that bacteria use to monitor cell-population density and coordinate group behaviors. QS relies on the production, detection, and group-wide response to extracellular signal molecules called ...
Amanda Hurley, Bonnie L Bassler
doaj   +1 more source

Living Microbial Drugs

Chemistry – A European Journal, EarlyView.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik, Nazlıcan Tunç, Senem Şen, Urartu Özgür Şafak Şeker   +3 more
wiley   +1 more source

Peptides as quorum sensing molecules : measurement techniques and obtained levels in vitro and in vivo [PDF]

, 2017
The expression of certain bacterial genes is regulated in a cell-density dependent way, a phenomenon called quorum sensing. Both Gram-negative and Gram-positive bacteria use this type of communication, though the signal molecules (auto-inducers) used by ...
Andersen, Asano, Bala, Baldrich, Balkwill, Bandyopadhaya, Barber, Barr, Barrett, Bart De Spiegeleer, Bassler, Baxter, Belleza, Beloin, Bultman, Campagna, Castro-Nallar, Cataldi, Cataldi, Charlesworth, Charlton, Chen, Chen, Chhabra, Chowers, Christophe Van de Wiele, Clarke, Cooley, Cryan, Darkoh, De Spiegeleer, De Spiegeleer, DiMango, Dolnick, Dunny, Eloe-Fadrosh, Engebrecht, Erdman, Erickson, Ernst, Evelien Wynendaele, Fekete, Finegold, Flavier, Frederick Verbeke, Freestone, Frommberger, Frommberger, Frommberger, Fuqua, Gomi, Gregus, Gupta, Haas, Higgins, Holden, Holzer, Hooi, Hughes, Håvarstein, Ike, Jahoor, Jiang, Junio, Kalia, Karavolos, Karavolos, Karavolos, Kaufmann, Kendall, Kolodkin-Gal, Kravchenko, Kravchenko, Kubesová, Kumar, Kumari, La Rosa, Li, Li, Li, Li, Lyte, Lyte, Lyte, Lyte, Malik, Marchesan, Mayer, McNab, Mello, Miyairi, Moos, Mori, Mori, Mori, Mori, Mori, Morin, Murray, Nakayama, Nakayama, Nakayama, Naseribafrouei, Nathan Debunne, Nealson, Nealson, Nilsen, O'Connor, O'Mahony, Oleskin, Oliver, Ortori, Pacheco, Parekh, Patel, Pearman, Pereira, Pesci, Pesci, Petersen, Pozzi, Pritchard, Pritchard, Procaccini, Rai, Rasko, Raut, Rickard, Rickard, Rutherford, Ryan, Severine De Craemer, Shaw, Sifri, Singh, Skindersoe, Smith, Smith, Smith, Spencer, Sperandio, Steindler, Stilling, Struss, Sturme, Suzuki, Syvitski, Taga, Tateda, Telford, Telford, Teplitski, Thaiss, Thiel, Thomas, Tian, Todd, Tomova, van der Meer, Vikström, Wagner, Wang, Wei, Wynendaele, Wynendaele, Wynendaele, Yamashita, Yorick Janssens, Zackular, Zhang, Zhou, Zhou, Zimmermann   +172 more
core   +2 more sources

Quorum Sensing Autoinducer-3 Finally Yields to Structural Elucidation [PDF]

ACS Central Science, 2020
A novel quorum sensing autoinducer, which regulates virulence in enterohemorrhagic Escherichia coli, had eluded structural characterization—until now.
Delmis E. Hernandez, Herman O. Sintim
openaire   +2 more sources

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Emergence of Continents Stabilized the Bioavailability of Boron

Terra Nova, EarlyView.
ABSTRACT Boron is an essential element for the development of life on Earth; borates stabilize ribose in prebiotic reactions and facilitate metabolism in higher plants. There is, however, a relatively narrow surface boron concentration range over which borates stabilize and serve as a micronutrient rather than a toxin.
Brendan V. Dyck, Jon Wade
wiley   +1 more source