Results 191 to 200 of about 5,018,411 (238)
Behcet′s Disease: Autoimmune or Autoinflammatory?
Journal of Ophthalmic & Vision Research, 2013 Alireza Hedayatfar
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Clinical and Genetic Spectrum of Nine Cases of NLRP3-Associated Autoinflammatory Disease (NLRP3-AID) and Identification of One Novel NLRP3 Mutation by Genetic Variation Analyses. [PDF]
J Immunol ResShangguan Y +8 more
europepmc +1 more source
Systemic autoinflammatory diseases
Journal of Autoimmunity, 2020 Systemic autoinflammatory diseases (SAIDs) are a growing group of disorders caused by a dysregulation of the innate immune system leading to episodes of systemic inflammation. In 1997, MEFV was the first gene identified as disease causing for Familial Mediterranean Fever, the most common hereditary SAID.
Julie Krainer +2 more
exaly +3 more sources
Antiviral TRIMs: friend or foe in autoimmune and autoinflammatory disease? [PDF]
Nature Reviews Immunology, 2011 The concept that viral sensing systems, via their ability to drive pro-inflammatory cytokine and interferon production, contribute to the development of autoimmune and autoinflammatory disease is supported by a wide range of clinical and experimental ...
Claire Wynne +2 more
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Autoinflammatory Bone Diseases [PDF]
Rheumatic Disease Clinics of North America, 2013 Autoinflammatory bone disease is a new branch of autoinflammatory diseases caused by seemingly unprovoked activation of the innate immune system leading to an osseous inflammatory process. The inflammatory bone lesions in these disorders are characterized by chronic inflammation that is typically culture negative with no demonstrable organism on ...
Polly J Ferguson
exaly +3 more sources
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Update on autoinflammatory diseases
Current Opinion in Rheumatology, 2023Purpose of review Although the concept of systemic autoinflammatory diseases (SAIDs) is still very young, our knowledge about them is exponentially growing. In the current review, we aim to discuss novel SAIDs and autoinflammatory pathways discovered in the last couple of years. Recent findings
Kosar Asna, Ashari +2 more
openaire +2 more sources
Best Practice & Research Clinical Rheumatology, 2008
Autoinflammatory diseases (AIDs) are illnesses caused by primary dysfunction of the innate immune system. Proteins that are mutated in AIDs mediate the regulation of NFkappaB activation, cell apoptosis, and IL-1beta secretion through cross-regulated and sometimes common signaling pathways.
Touitou, I., Kone-Paut, I.
openaire +2 more sources
Autoinflammatory diseases (AIDs) are illnesses caused by primary dysfunction of the innate immune system. Proteins that are mutated in AIDs mediate the regulation of NFkappaB activation, cell apoptosis, and IL-1beta secretion through cross-regulated and sometimes common signaling pathways.
Touitou, I., Kone-Paut, I.
openaire +2 more sources
Updates on autoinflammatory diseases
Current Opinion in Immunology, 2018Autoinflammatory diseases are hyperinflammatory, immune dysregulatory diseases caused by innate immune cells dysregulation that present typically in the perinatal period with systemic and organ-targeted inflammation, but with improved genetic testing and the development of diagnostic criteria, milder and later-onset forms are being detected in ...
Narcisa, Martinez-Quiles +1 more
openaire +2 more sources