Results 131 to 140 of about 165,261 (263)
Inflammatory niches as spatial drivers of disease mechanisms and targets for personalized treatment
Journal of the European Academy of Dermatology and Venereology, EarlyView.This study provides a comprehensive review of how spatial transcriptomics reveals disease‐specific inflammatory niches across multiple skin disorders, highlighting key immune–stromal, neuro–immune and metabolic interactions that were previously unappreciated in non‐spatial analyses. Abstract Disease states are increasingly recognized as being shaped by
Rundong Jiang +3 more
wiley +1 more source
Response to: ‘Autoinflammatory disease damage index (ADDI): a possible newborn also in hidradenitis suppurativa daily practice’ by Damiani et al [PDF]
, 2017 Kim V. Annink +2 more
openalex +1 more source
Annals of the New York Academy of Sciences, EarlyView.ABSTRACT Diagnosing systemic juvenile idiopathic arthritis (sJIA) poses significant challenges. Accumulating evidence has indicated that tRNA‐derived fragments (tRFs) play integral roles in the pathogenesis of numerous diseases. Plasma samples were collected from individuals diagnosed with sJIA and healthy controls (HCs) from two medical centers and ...
Jiqian Huang +6 more
wiley +1 more source
Pediatric Rheumatology Online JournalBackground Global healthcare disparities, stemming from organizational differences in healthcare systems, lead to variable availability and funding, resulting in a gap between recommended and implemented practices for interleukin (IL)-1-mediated ...
Marija Jelusic +14 more
doaj +1 more source
Fatal Chronic Varicella‐Zoster Viral Infection in a Young Man With Chediak–Higashi Syndrome
Pediatric Dermatology, EarlyView.ABSTRACT Chediak–Higashi syndrome (CHS) is a rare autosomal recessive primary immunodeficiency characterized by partial oculocutaneous albinism, neurologic involvement, and a predisposition to severe infections. Patients are particularly susceptible to developing hemophagocytic lymphohistiocytosis (HLH), which significantly worsens prognosis. We report
Albane Badet +4 more
wiley +1 more source
Systemic autoinflammatory diseases in pediatric population
, 2022 Maria Luís Marques +4 more
openalex +1 more source
A febrile papulovesicular rash in a patient with pyoderma gangrenosum
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Anika Rajput Khokhar +5 more
wiley +1 more source
Bilateral Idiopathic Pyoderma Gangrenosum: A Case Report of an Atypical Presentation
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT Pyoderma gangrenosum (PG) is a rare non‐infectious neutrophilic dermatosis which is characterized by a rapidly progressive, painful ulcer. Bilateral manifestation of PG is exceptionally rare and can easily be misdiagnosed as infection or vascular ulceration, delaying proper treatment.
Sanjog Thapa Magar +4 more
wiley +1 more source
European Journal of Immunology, Volume 56, Issue 2, February 2026.Phagocytosis of yeast activates recruitment of proteases and trafficking factors from the secretory and endosomal pathways to the IRAP compartment and subsequently phagosomes, promoting cross‐presentation. In the absence of Sec22b, IRAP endosome and phagosome maturation to late endosomes is accelerated.
Alice Senni +7 more
wiley +1 more source