Evaluation of Serum Zonulin Levels and Intestinal Permeability in Hidradenitis Suppurativa Patients
ABSTRACT Background Hidradenitis Suppurativa (HS) is a chronic inflammatory skin disease. Zonulin is a signaling protein secreted by enterocytes that regulates the function of tight junction complexes and intestinal permeability. The levels of zonulin increase in the blood with the disruption of the intestinal barrier and it is used as a biomarker ...
Elif Çetinkaya +7 more
wiley +1 more source
Attempts to identify the molecular cause of autoinflammatory recurrent fever
Systemic autoinflammatory diseases caused by dysregulation of the innate immunity are a known cause of recurrent fevers. We present the molecular diagnosis results of 12 children with recurrent fever, analyzing the correlation between molecular findings ...
Diana Savkiv, Oksana Boyarchuk
core +1 more source
The pyrin inflammasome, a leading actor in pediatric autoinflammatory diseases. [PDF]
La Bella S +7 more
europepmc +1 more source
ABSTRACT Background ReCell autologous cell transplantation demonstrates efficacy in vitiligo repigmentation. Traditional Chinese medicine, such as Quchong Banjiuju Pill, may synergize with ReCell to enhance results, though combined protocols remain underexplored. Aims This study evaluated the efficacy and safety of ReCell combined with Quchong Banjiuju
Qiao Chen +8 more
wiley +1 more source
Immune endotypes in tuberculosis: Keys to decoding disease complexity
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor +4 more
wiley +1 more source
PECU: A multicenter study on pediatric patients with cold‐induced urticaria
Abstract Background Cold‐induced urticaria (ColdU) is a rare chronic inducible urticaria that can cause systemic reactions, including cold‐induced anaphylaxis (ColdA), but pediatric data are limited. The aim of this study was to evaluate the clinical characteristics, comorbidities, management approaches, risk of anaphylaxis, and long‐term course of ...
Betul Gemici Karaaslan +59 more
wiley +1 more source
Editorial: The role of innate immunity in the pathogenesis of autoimmune and autoinflammatory diseases. [PDF]
Carmona-Rivera C +3 more
europepmc +1 more source
Implications of combined NOD2 and other gene mutations in autoinflammatory diseases. [PDF]
Nomani H +8 more
europepmc +1 more source
Renal Impairment Associated with Autoinflammatory Diseases
Kidney is one of the key target organs involved in autoinflammatory diseases (AIDs). The clinical manifestations of renal impairment associated with AIDs are diverse, including hematuria, proteinuria, nephrotic syndrome, hypertension, renal artery ...
JIAN Shan +3 more
core +1 more source
Pharmacologic management of renal involvement in monogenic autoinflammatory diseases. [PDF]
Fayed A +4 more
europepmc +1 more source

