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Stem Cell Transplantation As A Dynamical System: Are Clinical Outcomes Deterministic? [PDF]
Frontiers in Immunology (2014). 5:613, 2014 Outcomes in stem cell transplantation (SCT) are modeled using probability theory. However the clinical course following SCT appears to demonstrate many characteristics of dynamical systems, especially when outcomes are considered in the context of immune reconstitution.
arxiv +1 more source
Survival Prediction of Children Undergoing Hematopoietic Stem Cell Transplantation Using Different Machine Learning Classifiers by Performing Chi-squared Test and Hyper-parameter Optimization: A Retrospective Analysis [PDF]
, 2022 Bone Marrow Transplant, a gradational rescue for a wide range of disorders emanating from the bone marrow, is an efficacious surgical treatment. Several risk factors, such as post-transplant illnesses, new malignancies, and even organ damage, can impair long-term survival. Therefore, technologies like Machine Learning are deployed for investigating the
arxiv +1 more source
Physiological conditions influencing regenerative potential of stem cells [PDF]
, 2016 Stem cells are being used in the treatment of cardivovascular diseases. Here, we review the physiologic and pathologic conditions that impact the regenerative potential of stem cells in the treatment of cardiovascular diseases which include the influence
Avitabile, Daniele +3 more
core +1 more source
Endogenous musculoskeletal tissue engineering - a focused perspective [PDF]
, 2012 Two major difficulties facing widespread clinical implementation of existing Tissue Engineering (TE) strategies for the treatment of musculoskeletal disorders are (1) the cost, space and time required for ex vivo culture of a patient’s autologous cells ...
Adam, Clayton
core +2 more sources
Collective effects in flow-driven cell migration [PDF]
arXiv, 2023 Autologous chemotaxis is the process in which cells secrete and detect molecules to determine the direction of fluid flow. Experiments and theory suggest that autologous chemotaxis fails at high cell densities because molecules from other cells interfere with a given cell's signal.
arxiv
Annals of Medicine, 1996 Hodgkin's disease and non-Hodgkin's lymphomas can be treated and, in a large number of cases, cured by first-line chemotherapy or radiotherapy. Unlike many other malignancies, relapse is not uniformly fatal but the treatment is usually markedly myelotoxic with the high doses of chemotherapy used in relapse.
Anthony H. Goldstone +1 more
openaire +3 more sources
HematologyTo evaluate whether patients with multiple myeloma (MM) could benefit from tandem autologous hematopoietic stem cell transplantation (auto-HSCT), PubMed, Embase, Web of Science and Cochrane Library databases were systematically searched, and 10 eligible ...
Hongtao Li +3 more
doaj +1 more source
Autologous hematopoietic stem cell transplantation in progressive severe multiple sclerosis
Annals of Indian Academy of Neurology, 2015 Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system (CNS), which is disabling and majorly involves younger population. Various available treatments in forms of immunomodulation are not very effective; however, stem cell ...
Awadh Kishor Pandit +2 more
doaj +1 more source
Bioscientific Review, 2021 Children with spastic cerebral palsy usually display an elevationin muscle tone,a decline in gross motor functional abilities,feeding problems and visual problems.Studies on stem cell treatment are in their early stages concerningitsefficacy forcerebral
Alaa Noureldeen Kora
doaj +1 more source
Hematopoietic progenitor cell content of vertebral body marrow used for combined solid organ and bone marrow transplantation [PDF]
, 1995 While cadaveric vertebral bodies (VB) have long been proposed as a suitable source of bone marrow (BM) for transplantation (BMT), they have rarely been used for this purpose. We have infused VB BM immediately following whole organ (WO) transplantation to
Ball, ED +6 more
core +1 more source