Results 91 to 100 of about 5,538 (201)

Tyrosine phosphorylation enhances activity of pneumococcal autolysin LytA [PDF]

open access: yes, 2014
For a long time tyrosine phosphorylation has been recognized as a crucial post translational regulatory mechanism in eukaryotes. However, only in the past decade has recognition been given to the crucial importance of bacterial tyrosine phosphorylation ...
Whittall, J., Standish, A., Morona, R.
core   +1 more source

Genetic studies on Clostridium acetobutylicum

open access: yes, 1982
Bibliography: leaves 149-181.The aim of this study involved the characterisation of the cellulolytic properties of Clostridium acetobutylicum and the development of a genetic transfer system for this organism.
Allcock, Errol Ralph
core  

Plasmid-encoded autolysin in Bacillus anthracis: modular structure and catalytic properties

open access: yes, 2002
This article cites 16 articles, 9 of which can be accessed free ...
Agnès Fouet   +2 more
core   +1 more source

Adaptation in a Fibronectin Binding Autolysin of Staphylococcus saprophyticus

open access: yesmSphere, 2017
Human-pathogenic bacteria are found in a variety of niches, including free-living, zoonotic, and microbiome environments. Identifying bacterial adaptations that enable invasive disease is an important means of gaining insight into the molecular basis of ...
Tatum D. Mortimer   +7 more
doaj   +1 more source

Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?

open access: yesMass Spectrometry Reviews, Volume 44, Issue 5, Page 715-756, September/October 2025.
Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley   +1 more source

A Water-Assisted Catalytic Mechanism in Glycoside Hydrolases Demonstrated on the Staphylococcus aureus Autolysin E

open access: yes, 2018
Autolysin E (AtlE), from Staphylococcus aureus, is a cell-wall-degrading enzyme that is a potential drug target. It is a member of the glycoside hydrolase (GH) class, enzymes that commonly have either two catalytic residues and hydrolyze their ...
Sara Pintar (5101283)   +5 more
core   +3 more sources

Comparison of Binax NOW urine antigen test and pneumococcal DNA assay using qPCR before and after nasopharyngeal swabbing in healthy Malawian children

open access: yesNew Microbes and New Infections, 2015
Diagnosis of invasive pneumococcal disease is challenging. We compared Binax NOW pneumococcal urinary antigen test with blood pneumococcal PCR in healthy Malawian children with and without pneumococcal carriage, and we found a high false-positive rate ...
E.A. Lees   +5 more
doaj   +1 more source

Exposure of Staphylococcus aureus to Targocil Blocks Translocation of the Major Autolysin Atl across the Membrane, Resulting in a Significant Decrease in Autolysis

open access: yes, 2018
Peptidoglycan (PG) and wall teichoic acid (WTA) are the major staphylococcal cell wall components, and WTA biosynthesis has recently been explored for drug development. Targocil is a novel agent that targets the TarG subunit of the WTA translocase (TarGH)
Suzanne Walker   +3 more
core   +1 more source

High Level Expression and Purification of Atl, the Major Autolytic Protein of Staphylococcus aureus

open access: yesInternational Journal of Microbiology, 2014
Staphylococcus aureus is a major human and animal pathogen. Autolysins regulate the growth, turnover, cell lysis, biofilm formation, and the pathogenicity of S. aureus. Atl is the major autolysin in S. aureus.
Vineet K. Singh
doaj   +1 more source

Streptococcus pneumoniae Deficient in Pneumolysin or Autolysin Has Reduced Virulence in Meningitis

open access: yes, 2008
Background: The role played by pneumolysin and autolysin in pneumococcal meningitis is poorly understood. Method: A rat model was used to investigate the disease, in which surgical implantation of a cisternal catheter allowed bacterial instillation and ...
Christopher J. Guerin (7582775)   +13 more
core  

Home - About - Disclaimer - Privacy