Results 71 to 80 of about 4,864 (173)

Critical role of a ferritin-like protein in the control of Listeria monocytogenes cell envelope structure and stability under β-lactam pressure. [PDF]

PLoS ONE, 2013
The human pathogen Listeria monocytogenes is susceptible to the β-lactam antibiotics penicillin G and ampicillin, and these are the drugs of choice for the treatment of listerial infections.
Agata Krawczyk-Balska, Magdalena Lipiak
doaj   +1 more source

Purification and Characterization of an Autolysin from Clostridium acetobutylicum [PDF]

Applied and Environmental Microbiology, 1981
A proteinaceous substance with antibiotic-like activity, resembling that of a bacteriocin, was isolated from an industrial-scale acetone-butanol fermentation of Clostridium acetobutylicum . The substance, purified by acetone precipitation, diethylaminoethyl cellulose chromatography, and polyacrylamide gel ...
J R, Webster, S J, Reid, D T, Jones, D R, Woods   +3 more
openaire   +2 more sources

The Emerging Role of Microbial Extracellular Vesicles in Neuroinflammation and Neurodegeneration

Medicine Bulletin, Volume 2, Issue 2, Page 231-238, March 2026.
ABSTRACT Neurodegenerative and neuropsychiatric disorders are increasingly viewed as systemic conditions shaped by interactions among peripheral immunity, microbiota, and the central nervous system. However, the mechanisms linking microbial activity to neuroinflammation and neurodegeneration remain poorly defined.
Julio Jesús Estrada‐Valbuena, Chao Li, Claudia M. Parra‐Giraldo, Raquel Martínez‐López   +3 more
wiley   +1 more source

The secreted staphylococcal biofilm protein Sbp forms biomolecular condensates in the presence of DNA

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Staphylococcus epidermidis is the leading cause of device‐related infections, primarily due to its ability to form biofilms, surface‐adherent bacterial communities that confer remarkable resistance to antibiotics and host defenses. Small basic protein, Sbp, is a 16‐kDa protein expressed by S.
P. Ethan Adkins, Alexander E. Yarawsky, Andrew B. Herr   +2 more
wiley   +1 more source

Emerging Biomedical Engineering Therapies for Infected Diabetic Foot Ulcers: Toward Antibacterial Functionalization and Pathology‐Responsive Regulation

Small Science, Volume 6, Issue 1, January 2026.
Infected diabetic foot ulcer endangers patients with high amputation, disability, mortality risks, and heavy medical burdens. This review analyzes its pathogenic factors, the limitations of current treatments, the breakthroughs of responsive antimicrobial biomaterials, and the challenge of multifunctional biomaterial innovations for further developing ...
Yaqi Yao, Mengyi Huang, Yuetong Li, Yiqi Lin, Junjie Dong, Jianhang Du, Aixia Zhai, Changlong Bi, Luoyuan Li   +8 more
wiley   +1 more source

Metagenomic and Phenotypic Insights Into Biofilm‐Forming Pathogens in Patients With Nosocomial Sepsis

BioMed Research International, Volume 2026, Issue 1, 2026.
Biofilm‐related infections significantly contribute to bacterial diseases, with estimates suggesting that at least 80% of such infections are associated with biofilms. These infections often involve opportunistic pathogens, which not only influence the type of infection but also impact the microenvironment by interacting with other polymicrobial ...
Haleema Sadia, Arshia Amin, Iftikhar Ahmed, Baisakhi Banerjee   +3 more
wiley   +1 more source

Molecular docking of the pneumococcal main autolysin (LytA) and deoxycholate ligand

Pakistan Journal of Pharmaceutical Sciences, 2020
In the Streptococcus pneumoniae, the N-acetylmuramoyl-l-alanine amidase known as LytA protein is a main autolysin and in the presence of sodium deoxycholate, it activates and breaks S. pneumoniae cell wall.
Ghanbar Mahmoodi Chalbatani, Samira Karimaei, Davoud Afshar, Solmaz Ohadian Moghadam, Habibollah Mahmoodzadeh, Masoumeh Amini, Mohammad Shirkhoda   +6 more
doaj   +1 more source

Mechanistic Landscape and Farm to Fork Control Strategies for Streptococcus suis: An Emerging Foodborne Threat

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Streptococcus suis (S. suis) is an emerging zoonotic agent that now rivals classical food‐borne pathogens in its global clinical burden of meningitis and septic shock. Recent epidemiological syntheses covering more than 30 countries now list over 1600 laboratory‐confirmed human cases with a pooled case‐fatality of about 12%, climbing beyond 18% in East
Wangyuan Yao, Meili Chen, Hongkai Ren, Qingqing Luo, Xuyuan Wang, Md. Akhtar, Zeeshan Ahmad Bhutta, Lianci Peng, Muhammad Yasir Nawaz, Mohammad Mehedi Hasan, Md. F. Kulyar, Rendong Fang, Zhong Peng   +12 more
wiley   +1 more source

Comparison of Binax NOW urine antigen test and pneumococcal DNA assay using qPCR before and after nasopharyngeal swabbing in healthy Malawian children

New Microbes and New Infections, 2015
Diagnosis of invasive pneumococcal disease is challenging. We compared Binax NOW pneumococcal urinary antigen test with blood pneumococcal PCR in healthy Malawian children with and without pneumococcal carriage, and we found a high false-positive rate ...
E.A. Lees, D.K.K. Ho, M. Guiver, L.A. Mankhambo, N. French, ED Carrol   +5 more
doaj   +1 more source

Adaptation in a Fibronectin Binding Autolysin of Staphylococcus saprophyticus

mSphere, 2017
Human-pathogenic bacteria are found in a variety of niches, including free-living, zoonotic, and microbiome environments. Identifying bacterial adaptations that enable invasive disease is an important means of gaining insight into the molecular basis of ...
Tatum D. Mortimer, Douglas S. Annis, Mary B. O’Neill, Lindsey L. Bohr, Tracy M. Smith, Hendrik N. Poinar, Deane F. Mosher, Caitlin S. Pepperell   +7 more
doaj   +1 more source