Results 51 to 60 of about 4,864 (173)

Role of autolysin in generating the pneumococcal purpura-producing principle [PDF]

Infection and Immunity, 1981
The results of four studies described in this paper support the idea that pneumococcal autolysin (N-acetylmuramyl-L-alanine amidase) plays a key role in generating the pneumococcal purpura-producing principle (PPP) from the bacterial cell wall. This conclusion is based on the observation that (i) concentrates of pneumococcal cell-free extracts prepared
C, Chetty, A, Kreger
openaire   +2 more sources

Tiny carriers, big impact: How Fusobacterium nucleatum extracellular vesicles drive oral diseases and beyond

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma, Jiahui Huang, Yitong Chen, Haoxuan Wang, Hang Zou, Wanghong Zhao, Zilong Deng   +6 more
wiley   +1 more source

The bias of experimental design, including strain background, in the determination of critical Streptococcus suis serotype 2 virulence factors. [PDF]

PLoS ONE, 2017
Streptococcus suis serotype 2 is an important porcine bacterial pathogen and emerging zoonotic agent mainly responsible for sudden death, septic shock, and meningitis. However, serotype 2 strains are genotypically and phenotypically heterogeneous. Though
Jean-Philippe Auger, Sarah Chuzeville, David Roy, Annabelle Mathieu-Denoncourt, Jianguo Xu, Daniel Grenier, Marcelo Gottschalk   +6 more
doaj   +1 more source

Role of Autolysins in the Killing of Bacteria by Some Bactericidal Antibiotics [PDF]

Journal of Bacteriology, 1971
The rapid lysis of Bacillus licheniformis NCTC 6346 and B. subtilis 168 trp caused by vancomycin and d -cycloserine can be inhibited by stopping protein synthesis.
H J, Rogers, C W, Forsberg
openaire   +2 more sources

Cell Envelope Remodeling and Lipid Metabolism Coordinate Extracellular Vesicle Output in Mycobacterium Tuberculosis

Journal of Extracellular Biology, Volume 5, Issue 6, June 2026.
ABSTRACT Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading global cause of death due to the pathogen's highly adaptive physiology and its ability to manipulate host immunity. Despite extensive study, our understanding of Mtb biology during infection remains incomplete, limiting the development of new diagnostics ...
José L. Serrano‐Mestre, Laura Lerma, Lucía Vázquez‐Iniesta, Vivian C. Salgueiro‐Toledo, Ainhoa Palacios, Sogol Alebouyeh, Andrea Doddi, Felix Elortza, Mikel Azkargorta, Leticia Sampedro, Estibaliz Atondo, Miguel Ángel Pacual‐Itoiz, Oren Mayer, Torin Westwood, William R. Jacobs Jr, Rafael Prados‐Rosales   +15 more
wiley   +1 more source

Enterococcus faecalis autolysin EpaU binds the enterococcal polysaccharide antigen via its teichoic acid-like repeats and modulates c-di-AMP signaling

mBio
The cell wall of the gram-positive bacterium Enterococcus faecalis is decorated with the enterococcal polysaccharide antigen (EPA), consisting of a core rhamnan backbone linked covalently with a strain-variable teichoic acid-like (TA) polymer.
Catherine T. Chaton, Nicholas R. Murner, Svetlana Zamakhaeva, Jeffrey S. Rush, Cameron W. Kenner, Alexander E. Yarawsky, Lei Huang, Parastoo Azadi, Andrew B. Herr, Natalia Korotkova, Konstantin V. Korotkov   +10 more
doaj   +1 more source

Some properties of autolysin of Clostridium saccharoperbutylacetonicum.

Agricultural and Biological Chemistry, 1982
A lytic enzyme activity (N-acetylmuramidase activity) was found in the supernatant fluid of an exponentially growing culture of Clostridium saccharoperbutylacetonicum (ATCC 13564). The same enzyme activity was also found in the autolysate of the cells and the isolated crude cell walls.
YOSHINO, Sadazo, OGATA, Seiya, HAYASHIDA, Shinsaku   +2 more
openaire   +2 more sources

Virulence Associated Morphology of Different Strains of Melissococcus plutonius, a Brood Pathogen of Honey Bees

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
This study explores the diversity in cell morphology and growth behaviours of three Melissococcus plutonius strains, the causative agent of European foulbrood, employing electron microscopy and expression analysis of glycan‐binding protein candidate genes. Our results illustrate the mechanism of cell separation and the formation of individual cocci and
Oleg Lewkowski, Gerd Hause, Silvio Erler
wiley   +1 more source

Structural basis of cell wall cleavage by a staphylococcal autolysin. [PDF]

PLoS Pathogens, 2010
The major autolysins (Atl) of Staphylococcus epidermidis and S. aureus play an important role in cell separation, and their mutants are also attenuated in virulence.
Sebastian Zoll, Bernhard Pätzold, Martin Schlag, Friedrich Götz, Hubert Kalbacher, Thilo Stehle   +5 more
doaj   +1 more source

Comprehensive and Comparative Transcriptional Profiling of the Cell Wall Stress Response in Bacillus subtilis

Molecular Microbiology, Volume 125, Issue 6, Page 506-545, June 2026.
Transcriptional profiling of the primary cell envelope stress response (CESR) of Bacillus subtilis exposed to a range of cell wall‐targeting antimicrobials, combining RNAseq and high‐resolution tiling arrays. We revealed the complexity of the CESR, the contribution of extracytoplasmic function sigma factors (ECFs) and two‐component signal transduction ...
Qian Zhang, Charlène Cornilleau, Lena Friebel, Sarah Spitzner, Raphael R. Müller, Doreen Meier, Pierre Flores, Cyprien Guérin, Pierre Nicolas, Diana Wolf, Vincent Fromion, Rut Carballido‐López, Thorsten Mascher   +12 more
wiley   +1 more source