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To the Editor: —In my professional life I have been flooded with the usual number of insults to intelligence both by mail and by the softspoken detail man. As a result, I have no doubt, of the active propaganda for reform carried on byThe Journal, these insults have lost a certain quality of "rawness" and become much more cleverly done.
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ACTION OF "AUTOLYSIN" ON MOUSE TUMORS [PDF]
The use of "autolysin" in the treatment of cancer has been so widely heralded, in both the lay and the professional press, 1 that it was deemed proper to conduct the following experiments in order to determine whether the preparation has any action on tumors in mice, the malignancy and clinical course of which are quite comparable to those of human ...
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Autolysins are endogenous cell wall degrading enzymes (CWDEs) in bacteria that remodel the peptidoglycan layer of its own cell wall. In the Bacillus subtilis genome, at least 35 autolysin genes have been identified.
Luotao Wang +10 more
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Characterization of LysBC17, a Lytic Endopeptidase from Bacillus cereus
Bacillus cereus, a Gram-positive bacterium, is an agent of food poisoning. B. cereus is closely related to Bacillus anthracis, a deadly pathogen for humans, and Bacillus thuringenesis, an insect pathogen.
Steven M. Swift +6 more
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Aqueous enzymatic protein and lipid release from the microalgae Chlamydomonas reinhardtii
Advances in biochemical and molecular manipulation have led to increased biomass productivity and oil accumulation in the microalgae C. reinhardtii. However, scalable processes for the recovery of oil and other valuable biomolecules, such as protein ...
Laura Soto-Sierra +2 more
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Structural Organization of the Major Autolysin from Streptococcus pneumoniae [PDF]
LytA amidase is the best known bacterial autolysin. It breaks down the N-acetylmuramoyl-L-alanine bonds in the peptidoglycan backbone of Streptococcus pneumoniae and requires the presence of choline residues in the cell-wall teichoic acids for activity. Genetic experiments have supported the hypothesis that its 36-kDa chain has evolved by the fusion of
Usobiaga, P. +7 more
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In vitro bactericidal and bacteriolytic activity of ceragenin CSA-13 against planktonic cultures and biofilms of Streptococcus pneumoniae and other pathogenic streptococci. [PDF]
Ceragenin CSA-13, a cationic steroid, is here reported to show a concentration-dependent bactericidal/bacteriolytic activity against pathogenic streptococci, including multidrug-resistant Streptococcus pneumoniae.
Miriam Moscoso +3 more
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This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma +6 more
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Background: Infections due to Streptococcus pneumoniae are responsible for morbidity and mortality in a large proportion of children in developing countries where childhood vaccination has not been widely implemented. S.
Divya Suguna Jayakar +3 more
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The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut‐Lung Axis
ABSTRACT The gut‐lung axis constitutes a dynamic, multidirectional communication platform between the gastrointestinal and respiratory tracts. Its complexity arises from the integrated crosstalk among the microbiota, immune system, and redox homeostasis, collectively influencing disease susceptibility and progression.
Jian Kang +7 more
wiley +1 more source

