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Activity of the major staphylococcal autolysin Atl [PDF]
FEMS Microbiology Letters, 2006 The major autolysin of Staphylococcus aureus (AtlA) and of Staphylococcus epidermidis (AtlE) are well-studied enzymes. Here we created an atlA deletion mutant in S. aureus that formed large cell clusters and was biofilm-negative. In electron micrographs, the mutant cells were distinguished by rough outer cell surface.
Raja Biswas +2 more
exaly +3 more sources
Modular design of theEnterococcus hiraemuramidase-2 andStreptococcus faecalisautolysin [PDF]
FEMS Microbiology Letters, 1992 peer reviewedThe mature forms of the extracellular muramidase-2 of Enterococcus hirae and Streptococcus faecalis autolysin have very similar primary structures.
Bernard Joris +2 more
exaly +2 more sources
Indian Journal of Medical Microbiology, 2010 Purpose: To detect the presence of autolysin and pneumolysin genes among Streptococcus pneumoniae strains isolated from different disease entities among Indian patients. The study also attempted to determine antimicrobial susceptibility of the isolates.
R Kanungo +2 more
exaly +2 more sources
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A Computational Method for the Identification of Endolysins and Autolysins
Protein & Peptide Letters, 2020Background: Cell lytic enzyme is a kind of highly evolved protein, which can destroy the cell structure and kill the bacteria. Compared with antibiotics, cell lytic enzyme will not cause serious problem of drug resistance of pathogenic bacteria. Thus, the study of cell wall lytic enzymes aims at finding an efficient way for curing bacteria infectious.
Lei Xu +5 more
openaire +2 more sources
Prokaryotic Autolysin Database Construction
Proceedings of the 8th ACM International Conference on Bioinformatics, Computational Biology,and Health Informatics, 2017Databases are valuable resources that are capable of collecting and disseminating sizeable quantities of data with the purpose of furthering research done in that particular field. Currently, there are databases for organismal genomes and classes of proteins, but currently there is no database for bacterial autolysins in particular.
Brandon A. Saiz, Padmanabhan Mahadevan
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Bacterial growth — from physical principles to autolysins
Current Opinion in Microbiology, 2023For bacteria to increase in size, they need to enzymatically expand their cell envelopes, and more concretely their peptidoglycan cell wall. A major task of growth is to increase intracellular space for the accumulation of macromolecules, notably proteins, RNA, and DNA.
Yuki, Kitahara, Sven, van Teeffelen
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THE "AUTOLYSIN" TREATMENT FOR CANCER
Journal of the American Medical Association, 1915To the Editor: —In the Nov. 6, 1915, issue ofThe Journalthere was printed a special article by Dr. Richard Weil regarding the autolysin treatment of cancer. In this article Dr. Weil attempts to analyze the situation respecting autolysin, the method of its introduction in the General Memorial Hospital and the nature of the patients who were treated in ...
+4 more sources
1980
Among the earliest knowledge about microbes is the fact that cells, suspended and incubated under unfavourable conditions for growth and anabolism, disintegrate. Indeed autolysates of yeasts and other cells were some of the earliest sources of soluble enzymes, and did trojan work in the heroic days of the investigations of intermediary carbohydrate ...
H. J. Rogers, H. R. Perkins, J. B. Ward
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Among the earliest knowledge about microbes is the fact that cells, suspended and incubated under unfavourable conditions for growth and anabolism, disintegrate. Indeed autolysates of yeasts and other cells were some of the earliest sources of soluble enzymes, and did trojan work in the heroic days of the investigations of intermediary carbohydrate ...
H. J. Rogers, H. R. Perkins, J. B. Ward
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Autolysin as a fibronectin receptor on the cell surface of Clostridium perfringens
Anaerobe, 2023Clostridium perfringens causes food poisoning and gas gangrene, a serious wound-associated infection. C. perfringens cells adhere to collagen via fibronectin (Fn). We investigated whether the peptidoglycan hydrolase of C. perfringens, i.e., autolysin (Acp), is implicated in Fn binding to C.
Riyo, Aono +6 more
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1990
Cells of higher and lower plants are surrounded by a rigid cell wall, which is composed of elaborately intermeshed macromolecules. Growth, release and reproduction require a modification of this closely-knitted mesh-work.
S. Waffenschmidt, L. Jaenicke
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Cells of higher and lower plants are surrounded by a rigid cell wall, which is composed of elaborately intermeshed macromolecules. Growth, release and reproduction require a modification of this closely-knitted mesh-work.
S. Waffenschmidt, L. Jaenicke
openaire +1 more source