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Kinesin 1 Drives Autolysosome Tubulation
Developmental Cell, 2016 Autophagic lysosome reformation (ALR) plays an important role in maintaining lysosome homeostasis. During ALR, lysosomes are reformed by recycling lysosomal components from autolysosomes. The most noticeable step of ALR is autolysosome tubulation, but it
Qian Peter Su, Li Yu
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Cancers, 2019 Clinical use of the anti-cancer drug doxorubicin (DOX) is largely limited due to its severe cardiotoxicity. Dysregulation of autophagy is implicated in DOX-induced cardiotoxicity (DIC).
Mingyan Shao, Chun Li, Xiaoping Wang
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RAB2 regulates the formation of autophagosome and autolysosome in mammalian cells
Autophagy, 2019 Multiple sources contribute membrane and protein machineries to construct functional macroautophagic/autophagic structures. However, the underlying molecular mechanisms remain elusive.
Mei Mei, Xinyi Wang, Xiao Jiang
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Autophagy, 2013 Autophagy is a complex, multi-step and biologically important pathway mediated by autophagosomes and autolysosomes. Accurately dissecting and detecting different stages of autophagy is important to elucidate its molecular mechanism and thereby facilitate
Hao Chang, Juan Tang, Yang Hai
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An azacyclo-localizing fluorescent probe for the specific labeling of lysosome and autolysosome
Talanta, 2020Mingyong Han, Bianhua Liu, Zhenyang Wang
exaly
PI3P phosphatase activity is required for autophagosome maturation and autolysosome formation
EMBO Reports, 2014Hong Zhang, Xiaochen Wang, Shohei Mitani
exaly