Results 61 to 70 of about 3,685,912 (292)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
SensorsBackground. Automatic detection of Sit phases in people with Parkinson’s disease (PD) using a single body-worn sensor is crucial for enhancing long-term, home-based monitoring of mobility. Aim.
Etienne Goubault +5 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Using Dynamic Features for Automatic Cervical Precancer Detection
Diagnostics, 2021 Cervical cancer remains a major public health concern in developing countries due to financial and human resource constraints. Visual inspection with acetic acid (VIA) of the cervix was widely promoted and routinely used as a low-cost primary screening ...
Roser Viñals +5 more
doaj +1 more source
Automatic wheeze detection based on auditory modelling [PDF]
, 2005 Automatic wheeze detection has several potential benefits compared with reliance on human auscultation: it is experience independent, an automated historical record can easily be kept, and it allows quantification of wheeze severity. Previous attempts to
Y Qiu +7 more
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
An Automatic System for Remote Monitoring of Bactrocera dorsalis Population
AgricultureBactrocera dorsalis (Hendel, 1912) is a highly destructive pest affecting fruits and vegetables, making population monitoring essential for farmers to implement timely control measures.
Shao-Ping Chen +7 more
doaj +1 more source
The potential of Jellytoring 2.0 smart tool as a global jellyfish monitoring platform
Ecology and Evolution, 2022 Despite the recent recognition of jellyfish as an important component of marine ecosystems and existing concerns on their potential population increase, they are rarely monitored at the appropriate spatial and temporal scales.
Ana Ruiz‐Frau +4 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Space WeatherLarge‐scale traveling ionospheric disturbances (LSTIDs) are wave‐like structures propagating through the ionosphere from auroral to lower latitudes, affecting radar‐based technologies and satellite navigation.
Marco Guerra +8 more
doaj +1 more source