Results 81 to 90 of about 3,685,912 (292)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Automatic unhulled rice grain crack detection by X-ray imaging [PDF]

, 2007
Crack detection of incoming paddy (unhulled rice grain) is an important step in the rice milling industry, as paddy grains with cracks severely affect the milling yield.
Bal, Satish, Pothula, Anand Kumar
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Automatic Detection of Floating Ulva prolifera Bloom from Optical Satellite Imagery

Journal of Marine Science and Engineering
Annual outbreaks of floating Ulva prolifera blooms in the Yellow Sea have caused serious local environmental and economic problems. Rapid and effective monitoring of Ulva blooms from satellite observations with wide spatial-temporal coverage can greatly ...
Hailong Zhang, Quan Qin, Deyong Sun, Xiaomin Ye, Shengqiang Wang, Zhixin Zong   +5 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Automatically Detected Pecking Activity in Group-Housed Turkeys

Animals, 2020
In search for an early warning system for cannibalism, in this study a newly developed automatic pecking activity detection system was validated and used to investigate how pecking activity changes over the rearing phase and before cannibalistic ...
Jennifer J. Gonzalez, Abozar Nasirahmadi, Ute Knierim   +2 more
doaj   +1 more source

Automatic Detection of Laryngeal Pathology on Sustained Vowels Using Short-Term Cepstral Parameters: Analysis of Performance and Theoretical Justification [PDF]

, 2008
The majority of speech signal analysis procedures for automatic detection of laryngeal pathologies mainly rely on parameters extracted from time domain processing.
Juan Ignacio Godino-Llorente, Víctor Osma-Ruiz, Sáenz Lechón, Nicolas, Fraile Muñoz, Rubén, Nicolás Sáenz-Lechón, Gómez Vilda, Pedro, Pedro Gómez-Vilda, Godino Llorente, Juan Ignacio, Rubén Fraile, Osma Ruiz, Víctor   +9 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Detection System Design and Implementation for Foreign Objects in Automatic Platform Door Gap

Chengshi guidao jiaotong yanjiu
Objective The detection of foreign objects in platform door gap is critical to metro operational safety. Therefore, it is essential to develop a new anti-clamping detection system for metro platform door, enhancing the safety and efficiency of future FAO
YU Qingguang, WANG Shi, GAO Bonan, CHEN Yuxuan, XIAO Chengbo, LIU Youqi, WANG Yujin, ZHAO Ming, LI Le, CAI Guanzhi   +9 more
doaj   +1 more source