Results 111 to 120 of about 210,069 (312)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Converting Malfunctioned Fully Automatic (Electro-Mechanical Driven) to Semiautomatic Washing Machine

open access: yesJPAIR, 2013
This study converted a damaged fully automatic washing machine into a semi -automatic washing machine. Conversion of the machine was done due to unavailability of its electronic spare parts in the local market and to recycle the equipment.
Manuel A. Bajet, Jr.   +2 more
doaj   +1 more source

Automatic generation of robot and manual assembly plans using octrees

open access: yes, 2010
This paper aims to investigate automatic assembly planning for robot and manual assembly. The octree decomposition technique is applied to approximate CAD models with an octree representation which are then used to generate robot and manual assembly ...
Medellin, H.   +3 more
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Automatic Sequence-Based Network for Lung Diseases Detection in Chest CT. [PDF]

open access: yesFront Oncol, 2021
Hao J   +11 more
europepmc   +1 more source

Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America. [PDF]

open access: yes, 2015
The genome sequence of human herpesvirus 6A (HHV-6A) strain AJ was determined in a comparison of target enrichment and long-range PCR using next-generation sequencing methodologies.
Spyrou, MA   +5 more
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Re-searcher: a system for recurrent detection of homologous protein sequences

open access: yesBMC Bioinformatics, 2008
Background Sequence searches are routinely employed to detect and annotate related proteins. However, a rapid growth of databases necessitates a frequent repetition of sequence searches and subsequent analysis of obtained results.
Margelevičius Mindaugas   +2 more
doaj   +1 more source

Decimation-invariant sequences and their automaticity

open access: yesTheoretical Computer Science, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
André Barbé, Guentcho Skordev
openaire   +1 more source

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