Results 61 to 70 of about 210,069 (312)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Sequence‐to‐sequence transfer transformer network for automatic flight plan generation

IET Intelligent Transport Systems
In this work, a machine translation framework is proposed to tackle the flight plan generation in the air transport field. Diverging from the traditional human expert‐based way, a novel sequence‐to‐sequence transfer transformer network to automatic ...
Yang Yang, Shengsheng Qian, Minghua Zhang, Kaiquan Cai   +3 more
doaj   +1 more source

Quantification of Carotid Intraplaque Hemorrhage: Comparison between Manual Segmentation and Semi-Automatic Segmentation on Magnetization-Prepared Rapid Acquisition with Gradient-Echo Sequences

Diagnostics, 2019
Purpose: Carotid intraplaque hemorrhage (IPH) increases risk of territorial cerebral ischemic events, but different sequences or criteria have been used to diagnose or quantify carotid IPH. The purpose of this study was to compare manual segmentation and
Young Ju Song, Hyo Sung Kwak, Gyung Ho Chung, Seongil Jo   +3 more
doaj   +1 more source

Pseudorandom sequences derived from automatic sequences

Cryptography and Communications, 2022
Many automatic sequences, such as the Thue-Morse sequence or the Rudin-Shapiro sequence, have some desirable features of pseudorandomness such as a large linear complexity and a small well-distribution measure. However, they also have some disastrous properties in view of certain applications. For example, the majority of possible binary patterns never
László Mérai, Arne Winterhof
openaire   +3 more sources

Automatic test cases generation from software specifications modules [PDF]

, 2010
A new technique is proposed in this paper to extend the Integrated Classification Tree Methodology (ICTM) developed by Chen et al. [13] This software assists testers to construct test cases from functional specifications.
Alhroob, Aysh, Hossain, Alamgir, Dahal, Keshav   +2 more
core  

Cognitive control of sequential knowledge in 2-year-olds: evidence from an incidental sequence-learning and generation-task

, 2007
Thirty-eight two-year-olds were trained under incidental instructions on a six element deterministic sequence of spatial locations. Following training, participants were informed of the presence of a sequence and asked to either reproduce or suppress the
Bremner, Andrew J.; id_orcid, Bremner, Andrew, Kotsoni, E., Mareschal, Denis, Johnson, M.H., Cleeremans, Axel, Mareschal, D., Destrebecqz, Arnaud, Bremner, Andrew J., Csibra, Gergely   +9 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Automatic Album Sequencing

CoRR
Album sequencing is a critical part of the album production process. Recently, a data-driven approach was proposed that sequences general collections of independent media by extracting the narrative essence of the items in the collections. While this approach implies an album sequencing technique, it is not widely accessible to a less technical ...
Vincent Herrmann, Dylan R. Ashley, Jürgen Schmidhuber   +2 more
openaire   +2 more sources

Automatic Label Sequence Generation for Prompting Sequence-to-sequence Models

, 2022
Prompting, which casts downstream applications as language modeling tasks, has shown to be sample efficient compared to standard fine-tuning with pre-trained models.
Zhou, Jie, Gao, Tianyu, Lin, Yankai, Zhang, Zhengyan, Liu, Zhiyuan, Yu, Zichun, Sun, Maosong   +6 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source