Results 41 to 50 of about 278,863 (279)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

CFD Analysis of using Deionized Water in Radiator to Enhance the Efficiency for Sustainable Growth [PDF]

E3S Web of Conferences
Conventional liquid coolant used in automotive radiators is often used as an engine coolant. Heating systems in automotive air chambers are commonly used to cool circulating fluids, usually water or an aqueous combination of antifreeze agents such as ...
Vishwakarm Yogesh, Hayder Nibras, Srinivas Tummala, R J Anandhi, Jain Alok, Prakash Dwivedi Shashi, Kiran Ch. Ravi   +6 more
doaj   +1 more source

Active aerodynamics control of simplified vehicle body in a crosswind condition

The Journal of Engineering, 2020
In this study, the authors used a steady jet from a slit nozzle to control the bi-stable aerodynamics of a simple vehicle model under crosswind conditions.
Takuji Nakashima, Chao Yan, Chao Yan, Takashi Moriuchi, Itsuhei Kohri, Hidemi Mutsuda, Yasuaki Doi   +6 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Substantiation of Parameters of Cargo Movement by Car Rope Systems

Communications
The automobile cable systems for loading and unloading operations between the vehicle-support and vehicle-vehicle points are presented in this paper. The scheme of the automobile mobile cable system is based on a two-cable cableway. Based on this scheme,
Roman Rohatynskiy, Ivan Gevko, Oleg Lyashuk, Victor Aulin, Oleg Tson, Yuriy Nikerui, Andrii Horkunenko, Leonid Serilko, Bogdan Gevko, Olga Mosiy   +9 more
doaj   +1 more source

The Diesel Fuel Post-Injection into Engine Cylinder as Method of Nox Reduction

Communications, 2003
The possibilities of limiting the emission of nitrogen oxides in the cylinder of the diesel engine by means of its design and operating parameters are limited. This is why studies of the effectiveness of various methods for NOx reduction in exhaust gases
Zygmunt Szlachta, Jerzy Cisek
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Perception enhancement for steer-by-wire systems [PDF]

, 2005
Modern automobiles are safer and more comfortable than ever before. If there is one criticism that can be made, however, it is that the achievement of higher levels of comfort has sometimes come at the expense of a lack of driver involvement. The issue
Giacomin, J
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Vehicle driver identification system based on biometric data

Интеллект. Инновации. Инвестиции, 2020
The article discusses the problems associated with monitoring the observance of work and rest regimes by taxi drivers, which, together with an increase in the number of taxi services, lead to an increase in the number of road traffic accidents.
E. S. Kozin, A. V. Bazanov
doaj   +1 more source