Results 41 to 50 of about 15,411 (263)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Assessment of parameters of operability of inductor alternators of automobiles
Интеллект. Инновации. Инвестиции, 2019 The relevance of a problem of diagnosing of alternators is caused by insufficient informational content of the existing diagnosing methods. Automobiles can be equipped with inductor alternators, in which mainly electrical failures occur.
А.V. Puzakov, О.V. Yusupova
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Mathematical Modelling of Hybrid Powertrain Systems for Improved Energy Efficiency
CommunicationsThe development and simulation of a mathematical model for a hybrid powertrain vehicle, aiming to optimize its energy efficiency and dynamic performance is presented in this study.
Oleg Lyashuk +8 more
doaj +1 more source
Measuring Quality in Automobile Aftersales: AutoSERVQUAL Scale [PDF]
Amfiteatru Economic, 2017 It is becoming more important to accurately measure the level of quality in services and especially automobile related services such as after sales service.
Yasin Galip Gencer , Ulas Akkucuk
doaj
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
CFD Analysis of using Deionized Water in Radiator to Enhance the Efficiency for Sustainable Growth [PDF]
E3S Web of ConferencesConventional liquid coolant used in automotive radiators is often used as an engine coolant. Heating systems in automotive air chambers are commonly used to cool circulating fluids, usually water or an aqueous combination of antifreeze agents such as ...
Vishwakarm Yogesh +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Active aerodynamics control of simplified vehicle body in a crosswind condition
The Journal of Engineering, 2020 In this study, the authors used a steady jet from a slit nozzle to control the bi-stable aerodynamics of a simple vehicle model under crosswind conditions.
Takuji Nakashima +6 more
doaj +1 more source