Results 51 to 60 of about 278,863 (279)
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Automobile country of origin related associations in Lithuanian market [PDF]
Transport, 2007 Automobile is a high-involvement product that typically requires significant buyer’s attention when purchased. It is typical that country of origin (COO) of a purchased car is considered among other product characteristics. hough COO concept is analysed
S. Urbonavičius, V. Dikčius, R. Časas
doaj
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
HistoriesA key question in the literature of technology in society is the degree to which technology is a product of society and vice versa. A related question is how the differing cross-causal lines between the two change both technological and social forms ...
Cameron Elliott Gordon
doaj +1 more source
Estimation of contact characteristics based on measurement of inner tire surface strain
Nihon Kikai Gakkai ronbunshu, 2014 From a point of view of handling and stability, it is important to bring automotive tires into contact with the road correctly. If the contact state of the tire is known while moving, more advanced vehicle control can be carried out.
Shigeyuki YAMABE +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Light-Fueled Self-Propulsion of Liquid Crystal Elastomer-Engined Automobiles in Zero-Energy Modes
MathematicsThe defining attribute of self-excited motion is its capability to extract energy from a stable environment and regulate it autonomously, making it an extremely promising innovation for microdevices, autonomous robotics, sensor technologies, and energy ...
Zongsong Yuan +3 more
doaj +1 more source
Adaptive embedded control of cyber-physical systems using reinforcement learning
IET Cyber-Physical Systems, 2017 Embedded control parameters of cyber-physical systems (CPS), such as sampling rate, are typically invariant and designed with a worst case scenario in mind.
Hamid Mirzaei Buini +2 more
doaj +1 more source
"Automobiles: Strategy-based Lean Production System" [PDF]
The present situations and future prospects of the Japanese automobile industry are discussed. Selected topics in this paper include the following: analyses of the basic product-industry characteristics of the automobile (e.g., product architecture); the
Akira Tateishi, Takahiro Fujimoto
core