Results 51 to 60 of about 39,429 (218)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Research on Game Confrontation of Unmanned Surface Vehicles Swarm Based on Multi-Agent Deep Reinforcement Learning

水下无人系统学报
Based on the background of future modern maritime combats, a multi-agent deep reinforcement learning scheme was proposed to complete the cooperative round-up task in the swarm game confrontation of unmanned surface vehicles (USVs).
Changdong YU, Xinyang LIU, Cong CHEN, Dianyong LIU, Xiao LIANG   +4 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam, Anthony Siming Chen, Guido Herrmann   +2 more
wiley   +1 more source

PriorFusion: Unified integration of priors for robust road perception in autonomous driving

Communications in Transportation Research
With the growing interest in autonomous driving, there is an increasing demand for accurate and reliable road perception technologies. In complex environments without high-definition map support, autonomous vehicles must independently interpret their ...
Xuewei Tang, Mengmeng Yang, Tuopu Wen, Peijin Jia, Le Cui, Mingshan Luo, Kehua Sheng, Bo Zhang, Kun Jiang, Diange Yang   +9 more
doaj   +1 more source

CFD prediction of submarine motion during emergency surfacing

Zhongguo Jianchuan Yanjiu, 2019
[Objectives] Emergency surfacing is an important aspect of submarine vitality which is closely related to submarine safety. In order to master the motion laws of submarine during emergency surfacing performance,[Methods] this paper establishes a ...
LI Rijie, CHEN Qinglong, CHANG Wentian
doaj   +1 more source

Recycling of NiTi Shape Memory Alloys: Fundamental and Technological Aspects of a Vacuum Induction Melting Processing Route

Advanced Engineering Materials, EarlyView.
The present study investigates recycling of NiTi shape memory alloys via vacuum induction melting. An ingot was synthesized from elemental Ni and Ti and subjected to three subsequent remelting cycles. Remelting increases process durations and impurity levels and adversely affects microstructures and functional properties.
Sakia Sophia Noorzayee, Son Tung Mai, Sarath Menon, Braulio Gadiel Sánchez Ortega, Ralf Drautz, Alexander Kauffmann, Gunther Eggeler, Jan Frenzel   +7 more
wiley   +1 more source

Mass Platooning: Information Networking Structures for Long Platoons of Connected Vehicles

IEEE Open Journal of Intelligent Transportation Systems
Investigating Vehicle-to-everything (V2X) communication, we dive into the concept of vehicle platoons, a key innovation in transport systems, introducing a new era of cooperative driving.
Mahdi Razzaghpour, Babak Ebrahimi Soorchaei, Rodolfo Valiente, Yaser P. Fallah   +3 more
doaj   +1 more source

A single acoustic beacon-based positioning method for underwater mobile recovery of an AUV

International Journal of Advanced Robotic Systems, 2018
This article presents a navigation method for an autonomous underwater vehicle being recovered by a human-occupied vehicle. The autonomous underwater vehicle is considered to carry underwater navigation sensors such as ultra-short baseline, Doppler ...
Ziye Zhou, Yanqing Jiang, Ye Li, Cao Jian, Yeyi Sun   +4 more
doaj   +1 more source