Results 51 to 60 of about 2,115,919 (388)
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
(Im)possibilities of Autonomy: Social Movements In and Beyond Capital, the State and Development [PDF]
, 2008 Recently, we have witnessed the emergence of what appears to be a new set of claims in contemporary social movements based around the idea of autonomy. In this paper we interrogate this demand for autonomy.
Boehm, Steffen +2 more
core
COGNITIVE AND STYLE PREDICTORS OF THE STUDENTS’ PSYCHOLOGICAL WELL-BEING
International Journal of Cognitive Research in Science, Engineering and Education, 2020 The article analyses the psychological well-being and basic beliefs of students from the point of view of various variables, but the particular attention is payed to cognitive style, which is studied as the way of information assessment, determining ...
Irina Kibal’chenko A. +1 more
doaj +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
The American Journal of Bioethics, 2016 Taken as such, default rules do not intrude on autonomy, even if they influence people without persuading them. When default rules give people certain rights automatically (such as the right to vote), they promote autonomy for just that reason. And to the extent that default rules give people the freedom to focus on their most pressing concerns, they ...
openaire +4 more sources
Is there Space for "Genuine Autonomy" for Tibetan Areas in the PRC's System of Nationalities Regional Autonomy? [PDF]
, 2010 This article considers whether room exists within the current system of nationalities regional autonomy (NRA) in China to accommodate Tibetan aspirations for "genuine autonomy" under the People's Republic of China (PRC) sovereignty. It examines the legal
Ghai, Y., Loper, Kelley, Woodman, Sophia
core +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
How Autonomy Can Legitimate Beneficial Coercion [PDF]
, 2017 Respect for autonomy and beneficence are frequently regarded as the two essential principles of medical ethics, and the potential for these two principles to come into conflict is often emphasised as a fundamental problem.
White, Lucie
core
, 2017 Autonomous surgery involves having surgical tasks performed by a robot operating under its own will, with partial or no human involvement. There are several important advantages of automation in surgery, which include increasing precision of care due to ...
Das, Nikhil, Yip, Michael
core +1 more source