Results 61 to 70 of about 1,863,745 (359)

Autonomy, Behavior, & Moral Goodness [PDF]

open access: yes, 2003
In this essay, the view that autonomy is always a good is challenged. Numerous examples of autonomous people who committed quite immoral acts are offered.
Thomas, Professor Laurence
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Autonomy: Simulation's Next Events [PDF]

open access: yesProceedings of 1993 Winter Simulation Conference - (WSC '93), 1993
Simulation is facing the challenge to support ever increasingly complex phenomena characterized by autonomous behavior. This paper discusses an approach with which to investigate the wider modeling and analysis issues raised by these demand.
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Mixed Initiative Systems for Human-Swarm Interaction: Opportunities and Challenges

open access: yes, 2018
Human-swarm interaction (HSI) involves a number of human factors impacting human behaviour throughout the interaction. As the technologies used within HSI advance, it is more tempting to increase the level of swarm autonomy within the interaction to ...
Abbass, Hussein, Hussein, Aya
core   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

Validity of the Walked Distance Estimated by Wearable Devices in Stroke Individuals

open access: yesSensors, 2019
Background: Health professionals need valid devices to assess a stroke individual’s ability to walk. The aim was to evaluate the validity of the estimation of the walked distance by wearable devices and the impact of the sensor’s position in ...
Maxence Compagnat   +6 more
doaj   +1 more source

Defending a Rule of Institutional Autonomy on No-Harm Grounds [PDF]

open access: yes, 2004
The argument I sketch here for institutional autonomy is basically empirical and agrees with Professor Hamilton in making harm-reduction the overriding social goal. The argument proceeds in two steps.
Tushnet, Mark V.
core   +2 more sources

The Case for an Autonomy-Centred View of Physician-Assisted Death [PDF]

open access: yes, 2020
Most people who defend physician-assisted death (PAD) endorse the Joint View, which holds that two conditions—autonomy and welfare—must be satisfied for PAD to be justified. In this paper, we defend an Autonomy Only view.
Davis, Jeremy, Mathison, Eric
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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