Results 51 to 60 of about 547,940 (314)

Sustaining language learner well-being and flourishing: A mixed-methods study exploring advising in language learning and basic psychological need support

open access: yesPsychology of Language and Communication, 2022
The present study takes a self-determination theory perspective (Ryan & Deci, 2017) to explore the connections linking advising in language learning and basic psychological need satisfaction, and ways participation in advising can enhance learner well ...
Shelton-Strong Scott J.
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Autonomy and Authenticity of Enhanced Personality Traits

open access: yes, 2009
There is concern that the use of neuroenhancements to alter character traits undermines consumer's authenticity. But the meaning, scope and value of authenticity remain vague.
Bublitz, Jan Christoph, Merkel, Reinhard
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Insight Under Scrutiny in the Court of Protection: A Case Law Survey

open access: yesFrontiers in Psychiatry, 2020
The concept of patient insight, of a patient’s self-awareness of illness or impairment (and related issues), plays a significant role in clinical discourse and clinical practice.
Sándor Gurbai   +5 more
doaj   +1 more source

Autonomy and commerce: the integration of architectural autonomy

open access: yesArchitectural Research Quarterly, 2007
More than three decades ago, the architectural historian Manfredo Tafuri pessimistically concluded that a revolutionary architecture cannot precede a social revolution. In this comment, he summed up the perceived failure of Modernist architecture to realise a social utopia.
openaire   +3 more sources

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Temporal Graph Traversals Using Reinforcement Learning With Proximal Policy Optimization

open access: yesIEEE Access, 2020
Graphs in real-world applications are dynamic both in terms of structures and inputs. Information discovery in such networks, which present dense and deeply connected patterns locally and sparsity globally can be time consuming and computationally costly.
Samuel Henrique Silva   +2 more
doaj   +1 more source

Autonomie of relationele autonomie?

open access: yesNederlands Tijdschrift voor Geneeskunde, 2020
Het is een veelvoorkomend misverstand te denken dat het begrip ‘respect voor de autonomie’ betekent dat de patiënt altijd alleen moet beslissen en dat alles wat de patiënt wenst ook moet gebeuren, zonder grenzen. Ook aan het klassieke begrip ‘respect voor autonomie’ zitten grenzen; vrijheid houdt op waar anderen geschaad worden. Bovendien is het begrip
van de Vathorst, Suzanne   +1 more
openaire   +2 more sources

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

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